Neonatal Subgaleal Hemorrhage: Narrative Review
https://doi.org/10.15690/vsp.v24i3.2901
Abstract
Subgaleal hemorrhage (SH) is a blood pooling between epicranial aponeurosis and skull bones periosteum. It is a fluctuating mass on the scalp spreading through the cranial sutures. Children with SH may have anemia, hyperbilirubinemia, pain syndrome, and seizures. Newborns with SH may require monitoring and treatment in intensive care unit. Ophthalmoplegia, eyelid ptosis, and visual impairment are possible if SH is spreading to the orbital region. In case of large SH, blood can penetrate below zygomatic arch, thus, the child may have difficulties with breathing, apnea, and soft tissue necrosis. Up to 250–300 ml of blood can accumulate in subaponeurotic space in newborns. Therefore, large SH may lead to hypovolemia, arterial hypotension, coagulopathy, and hemorrhagic shock. Children with SH may have subdural hematomas, cerebellar tentorium ruptures, skull fractures. Mortality rate among infants with SH admitted to intensive care unit is 12–14%. Differential diagnosis should be performed with cephalhematoma and large caput succedaneum. Ultrasound examination allows us to differentiate these conditions, determine further tactics of instrumental imaging and patient management. Neonatologists, intensivists, and pediatricians can master the ultrasound examination technique in children. Small SH can reabsorb on their own within few weeks. Surgical treatment may be required in case of large hemorrhages due to the high risk of complications (suppuration, necrosis, calcifications, and visual impairments).
About the Author
Andrey F. KiosovRussian Federation
Saint Petersburg
Disclosure of interest:
None
References
1. Babata K, Vadlamudi G, Bailey NA, et al. Subgaleal hemorrhage in neonates: a comprehensive review and summary recommendations. J Perinatol. 2025;45(2):167-179. doi: https://doi.org/10.1038/s41372-024-02116-w
2. Baev OR, Gaidarova AR, Karavaeva AL. Birth trauma of newborns. Neonatologiya: novosti, mneniya, obuchenie = Neonatology: news, opinions, education. 2023;11(2):67-73. (In Russ). doi: https://doi.org/10.33029/2308-2402-2023-11-2-67-73
3. Ojumah N, Ramdhan RC, Wilson C, et al. Neurological Neonatal Birth Injuries: A Literature Review. Cureus. 2017;9(12):e1938. doi: https://doi.org/10.7759/cureus.1938
4. Meng A, Purohith A, Huang A, et al. Traumatic Birth Injury in a Term Neonate. Cureus. 2022;14(12):e32737. doi: https://doi.org/10.7759/cureus.32737
5. Prevention, Detection and Management of Subgaleal Haemorrhage in the Newborn: Clinical Guidance Statement. Royal Australian and New Zealand College of Obstetricians and Gynaecologists; 2021. Available online: https://ranzcog.edu.au/wp-content/uploads/Subgaleal-Haemorrhage.pdf. Accessed on April 21, 2025.
6. Christensen TR, Bahr TM, Henry E, et al. Neonatal subgaleal hemorrhage: twenty years of trends in incidence, associations, and outcomes. J Perinatol. 2023;43(5):573-577. doi: https://doi.org/10.1038/s41372-022-01541-z
7. Patchana T, Ghanchi H, Taka T, et al. Subgaleal hematoma evacuation in a pediatric patient: A case report and review of the literature. Surg Neurol Int. 2020;11(243):1-5. doi: https://doi.org/10.25259/SNI_207_2020
8. Colditz MJ, Lai MM, Cartwright DW, Colditz PB. Subgaleal haemorrhage in the newborn: A call for early diagnosis and aggressive management. J Paediatr Child Health. 2015;51(2): 140-146. doi: https://doi.org/10.1111/jpc.12698
9. Levin G, Mankuta D, Eventov-Friedman S, et al. Neonatal subgaleal hemorrhage unrelated to assisted vaginal delivery: clinical course and outcomes. Arch Gynecol Obstet. 2020;301(1):93-99. doi: https://doi.org/10.1007/s00404-019-05392-6
10. Bowens JP, Liker K. Subgaleal Hemorrhage Secondary to Child Physical Abuse in a 4-Year-Old Boy. Pediatr Emerg Care. 2021;37(12):e1738-e1740. doi: https://doi.org/10.1097/PEC.0000000000001937
11. Scheier E, Guri A, Balla U. Subgaleal haematoma due to hair pulling: Review of the literature. Acta Paediatr. 2019;108(12): 2170-2174. doi: https://doi.org/10.1111/apa.14971
12. Shamji S, Jacoby JL. Massive subgaleal hematoma and clinical suspicion of child abuse. J Am Osteopath Assoc. 2015;115(1):58; quiz 59-60. doi: https://doi.org/10.7556/jaoa.2015.014
13. Smith A, Kandamany N, Okafor I, et al. Delayed Infant Subaponeurotic (Subgaleal) Fluid Collections: A Case Series of 11 Infants. J Emerg Med. 2016;50(6):881-886. doi: https://doi.org/10.1016/j.jemermed.2016.03.024
14. Levin G, Mankuta D, Eventov-Friedman S, et al. Factors associated with the severity of neonatal subgaleal haemorrhage following vacuum assisted delivery. Eur J Obstet Gynecol Reprod Biol. 2020;245:205-209. doi: https://doi.org/10.1016/j.ejogrb.2019.12.012
15. Levin G, Elchalal U, Yagel S, et al. Risk factors associated with subgaleal hemorrhage in neonates exposed to vacuum extraction. Acta Obstet Gynecol Scand. 2019;98(11):1464-1472. doi: https://doi.org/10.1111/aogs.13678
16. Radovanović T, Spasojević S, Stojanović V, Doronjski A. Severe neonatal subgaleal hemorrhage as the first presentation of hemophilia A. Srp Arh Celok Lek. 2016;144(3-4):204-206.
17. Stephan AM, Feldman KW, Otjen JP, Metz JB. Delayed Subaponeurotic Fluid Collections: A Benign Cause of Scalp Swelling in Infancy. Pediatr Emerg Care. 2021;37(7):e408-e411. doi: https://doi.org/10.1097/PEC.0000000000001720
18. Talar T, Pacześniak U, Nowiczewski M, et al. Subgaleal hematoma as a perinatal presentation of rare hematologic problems in newborns. Own experience. Dev Period Med. 2015;19(3 Pt 1):277-282.
19. Inacio R, Saldanha J. Raccoon eyes in a newborn. Fetal Pediatr Pathol. 2022;41(4):701-703. doi: https://doi.org/10.1080/15513815.2021.1948152
20. Kim SY, Cha HG, Jang SY, Hwang SC. Delayed Massive Expansion of Subgaleal Hematoma Complicated with Proptosis in Hemophilia B. Korean J Neurotrauma. 2021;17(2):149-155. doi: https://doi.org/10.13004/kjnt.2021.17.e14
21. Andresen F, Zieger B, Würtemberger U, Kunze M, Hentschel R. The Neonatal Subgaleal Hematoma — A Neonatal Emergency. Z Geburtshilfe Neonatol. 2021;225(6):529-533. doi: https://doi.org/10.1055/a-1498-2817
22. El-Dib M, Parziale MP, Johnson L, et al. Encephalopathy in neonates with subgaleal hemorrhage is a key predictor of outcome. Pediatr Res. 2019;86(2):234-241. doi: https://doi.org/10.1038/s41390-019-0400-1
23. Levin G, Rosenbloom JI, Sultani M, et al. The role of sonographic head circumference in the occurrence of subgaleal hemorrhage following vacuum delivery. J Matern Fetal Neonatal Med. 2022;35(25):5450-5455. doi: https://doi.org/10.1080/14767058.2021.1882983
24. Esslami GG, Moienafshar A. Neonatal bilateral adrenal hemorrhage and adrenal insufficiency accompanied by Subgaleal hematoma: a case report with brief review of literature. BMC Pediatr. 2022;22(1):248. doi: https://doi.org/10.1186/s12887-022-03314-1
25. Chang HY, Cheng KS, Liu YP, et al. Neonatal infected subgaleal hematoma: an unusual complication of early-onset E. coli sepsis. Pediatr Neonatol. 2015;56(2):126-128. doi: https://doi.org/10.1016/j.pedneo.2013.03.003
26. Barry J, Fridley J, Sayama C, Lam S. Infected Subgaleal Hematoma Following Blunt Head Trauma in a Child: Case Report and Review of the Literature. Pediatr Neurosurg. 2015;50(4):223-228. doi: https://doi.org/10.1159/000433442
27. Salloum S, Sit W, Walton MM, Kamian K. Infected subgaleal hematoma in a 4-month-old girl. Am J Emerg Med. 2021;39:250. e5-250.e6. doi: https://doi.org/10.1016/j.ajem.2020.05.090
28. Cullas Ilarslan NE, Gunay F, Kaynak SS, et al. A rare cause of scalp swelling in infancy: delayed subaponeurotic fluid collections in five cases. Childs Nerv Syst. 2019;35(5):875-878. doi: https://doi.org/10.1007/s00381-018-04040-9
29. Wang S, Drake J, Kulkarni AV. Management and outcome of spontaneous subaponeurotic fluid collections in infants: the Hospital for Sick Children experience and review of the literature. J Neurosurg Pediatr. 2016;18(4):442-447. doi: https://doi.org/10.3171/2016.4.PEDS1641
30. Kefalogematoma pri rodovoi travme: Clinical recommendations. Russian Society of Neonatologists. Moscow: RSN; 2024. 27 p. (In Russ).
31. Kiosov AF. Cephalohematomas in children. Lechaschi Vrach. 2019;(10):52-55. (In Russ). doi: https://doi.org/10.26295/OS.2019.61.42.010
32. Kiosov AF, Galiaskarova AR. Risk factors and clinical features of the formation of cephalhematoma in newborns. Ural Medical Journal. 2019;(15):23-27. (In Russ). doi: https://doi.org/10.25694/URMJ.2019.15.07
33. Acuna J, Adhikari S. Point-of-care Ultrasound to Distinguish Subgaleal and Cephalohematoma: Case Report. Clin Pract Cases Emerg Med. 2021;5(2):198-201. doi: https://doi.org/10.5811/cpcem.2021.3.51375
34. Iova AS. Osobennosti vedeniya novorozhdennykh s kefalogematomami: individualizirovannyi podkhod i minimal'naya invazivnost'. StatusPraesens. Pediatriya i neonatologiya. 2020;(3/4):101-105. (In Russ).
35. Olkhova EB. Klinicheskie normy. Ul'trazvukovoe issledovanie v pediatrii: Methodological recommendations. Moscow: GEOTAR-Media; 2024. 288 p. (In Russ).
36. Vasiliev AY, Olkhova EB. Ultrasound diagnostics in emergency pediatric practice: A guide for doctors. In 2 vol. Vol. 1. 2nd edn., rev. and add. Moscow: GEOTAR-Media; 2024. 704 p. (In Russ).
Review
For citations:
Kiosov A.F. Neonatal Subgaleal Hemorrhage: Narrative Review. Current Pediatrics. 2025;24(3):140-145. (In Russ.) https://doi.org/10.15690/vsp.v24i3.2901