Preview

Current Pediatrics

Advanced search

EPIDEMIOLOGICAL AND CLINICAL PECULIARITIES OF ATOPIC DERMATITIS IN CHILDREN IN ENDEMIC REGION WITH OPISTHORCHIASIS

Abstract

The cross-sectional study of schoolchildren from Tomsk (the region with low prevalence of opisthorchiasis) and Tomsk region (rural places with high prevalence of opisthorchiasis) with Russian version of standardized questionnaire ISAAC was performed. The study included questionnaire poll and allergological diagnostics with standardized panel of allergens. Prevalence of atopic dermaitits (AtD) symptoms was not differing, but the peculiarities of clinical course of disease were revealed depending on the place of living and gender. The onset of AtD was earlier in schoolchildren from Tomsk compared to schoolchildren from rural places. Despite the absence of statistically significant differences in symptoms’ prevalence, the level of sensitizing in children from the city was much higher than in village (60% and 30% correspondingly, p<0,001). This fact shows modification of allergic inflammation during opisthorchiasis invasion and it needs further study.

Key words: children, atopic dermatitis, ISAAC, Opisthorchis felineus, sensitisation.
(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):50-53)

About the Authors

L.M. Ogorodova
Syberian State Medical University, Tomsk
Russian Federation



E.M. Kamaltynova
Syberian State Medical University, Tomsk
Russian Federation


I.A. Deev
Syberian State Medical University, Tomsk
Russian Federation



E.G. Belonogova
Syberian State Medical University, Tomsk
Russian Federation


O.S. Fedorova
Syberian State Medical University, Tomsk
Russian Federation



D.S. Gonsorunova
Syberian State Medical University, Tomsk
Russian Federation


S.B. Dugarova
Syberian State Medical University, Tomsk
Russian Federation


References

1. Hellriegel B. Immunoepidemiology – bridging the gap between immunology and epidemiology. Trends in Parasitology. 2001; 17 (2): 102–106.

2. Cooper P.J., Baretto M.L., Rodrigues L.C. Human allergy and geohelminth infections: a review of the literature and a proposed conceptual model to guide the investigation of possible causal associations. British Medical Bulletin. 2006; 79–80 (1): 203–218.

3. Dunne D. W., Riley E. M. Immunity, morbidity and immunoepidemiology in parasite infections. Parasite Immunology. 2004; 26: 425–428.

4. ISAAC Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet. 1998; 351: 1225–1232.

5. Weinmayr G., Weiland S., Bjorksten B. Atopic sensitization and the international variation of asthma symptom prevalence in children. Am. J. Respir. Crit. Care Med. 2007; 176 (6): 565–574.

6. Williams H., Stewart A., Mutius E. Is eczema really on the increase worldwide? J. Allergy Clin. Immunol. 2008; 121 (4): 947–954.

7. Куропатенко М.В., Желенина Л.А., Безушкина Р.А. и др. Диагностические особенности бронхиальной астмы у детей с паразитозами. Аллергология. 2006; 3: 10–20.

8. Strachan D.P. Hayfever, hygiene, and household size. BMJ. 1989; 299: 1259–1262.

9. Yazdanbakhsh M., Matricardi P.M. Parasites and the hygiene hypothesis: regulating the immune system? Clin. Rev. Allergy Immunol. 2004; 26 (1): 15–24.

10. Богова А.В., Ильина Н.И., Лусс Л.В. Тенденции в изучении эпидемиологии аллергических заболеваний в России за последние 10 лет. Российский аллерг. журнал. 2008; 6: 3–11.

11. Кондюрина Е.Г., Филатова Т.А., Елкина Т.Н. и др. Атопический дерматит у детей: современные эпидемиологические тенденции. Бюллетень СО РАМН. 2004; 1 (111): 39–44.

12. Черняк Б.А., Буйнова С.Н., Тяренкова С.В. Аллергические риниты у детей и подростков в Восточной Сибири: распространенность, этиологическая характеристика и взаимосвязь с бронхиальной астмой. Российская ринология. 1998; 4: 4–10.

13. Профилактика паразитарных болезней на территории Российской Федерации: Санитарные правила и нормы. М.: Минздрав России. 1997. С. 50–82.

14. Ogorodova L.M., Freidin M.B., Sazonov A.E. et al. A pilot screening of prevalence o atopic states and opisthorchiasis and their relationships in people of Tomsk oblast. Parasitology Research. 2007; 5: 80–83.

15. Евдокимова Т.А., Огородова Л.М. Влияние описторхозной инвазии на клиническое течение и иммунный ответ при атопической бронхиальной астме у детей. Педиатрия. 2005; 6: 12–17.

16. Гавалов С.М., Кондюрина Е.Г., Елкина Т.Н. и др. Стандартизированные эпидемиологические исследования аллергических заболеваний у детей. Адаптация программы «Международное исследование астмы и аллергии у детей («ISAAC»)» в России. Пособие для врачей. М. 1998. 30 с.

17. Балашева И.И., Миронова З.Г. Особенности течения и терапии описторхоза у детей. Томск: Томский университет. 1990. 152 с.

18. Огородова Л.М., Федорова О.С., Фрейдин М.Б. и др. Характеристика эпидемиологических и молекулярных взаимоотношений аллергических и гельминтных болезней в эндемическом очаге описторхоза. Бюллетень сибирской медицины. 2008; 4: 48–52.


Review

For citations:


Ogorodova L., Kamaltynova E., Deev I., Belonogova E., Fedorova O., Gonsorunova D., Dugarova S. EPIDEMIOLOGICAL AND CLINICAL PECULIARITIES OF ATOPIC DERMATITIS IN CHILDREN IN ENDEMIC REGION WITH OPISTHORCHIASIS. Current Pediatrics. 2010;9(3):50-53.

Views: 536


ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)