Preview

Current Pediatrics

Advanced search

EFFECTIVENESS OF CYCLOSPORINE IN SYSTEMIC TYPE OF JUVENILE IDIOPATHIC ARTHRITIS

Abstract

This is a case report of severe juvenile idiopathic arthritis in child, conditioned as by main disease as by inadequate hormonal treatment. Therapy with cyclosporine furthered development of clinical and laboratory remission of disease, inhibition of process of anatomical destruction and activation of reparation of femoral head, bone tissue in acetobular region of iliac and sciatic bones.

Key words: juvenile idiopathic arthritis, cyclosporine, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):147-150)

About the Authors

V.A. Kel’tsev
Samara State Medical University
Russian Federation


L.I. Grebenkina
Samara State Medical University
Russian Federation


References

1. Алексеева Е.И., Шахбазян И.Е. Принципы патогенетической терапии тяжелых системных вариантов ювенильного ревматоидного артрита. Серия: Аутоиммунные болезни. М. 2002. С. 127.

2. Кельцев В. А. Ювенильный идиопатический артрит. Самара: Содружество. 2005. 214 с.

3. Алексеева Е.И., Валиева С.И., Апаева Д.В. Эффективность и безопасность комбинированной иммуносупрессивной терапии Циклоспорином А и метотрексатом у больных тяжелым ювенильным ревматоидным артритом. Вопросы современной педиатрии (Приложение). 2006; 5 (2): 19–27.

4. Edmonds J., Scott D., Furst D. et al. Antirheumatic drugs: A proposed new classification. Arthritis Rheum. 1993; 36: 336–339.

5. Russell R. Bone Cell Biology. The role of cytokines and other mediators. Osteoporosis. Ed. R. Smith. London: Royal Colleg. of Physicians. 1990. P. 9.

6. Del Pozo E., Elford P., Perrelet R. et al. Prevention of adjuvant arthritis by cyclosporine in rats. Sem. Arthr. Rheum. 1992; 21 (3): 23.


Review

For citations:


Kel’tsev V., Grebenkina L. EFFECTIVENESS OF CYCLOSPORINE IN SYSTEMIC TYPE OF JUVENILE IDIOPATHIC ARTHRITIS. Current Pediatrics. 2010;9(3):147-150.

Views: 566


ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)