EFFICACY AND SAFETY OF PROLONGED TREATMENT WITH CYCLOSPORINE IN CHILDREN WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS
Abstract
Key words: children, focal segmental glomerulosclerosis, cyclosporine, methylprednisolone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4):155-159)
About the Authors
O.V. KomarovaRussian Federation
M.V. Matveeva
Russian Federation
A.N. Tsygin
Russian Federation
L.V. Leonova
Russian Federation
A.G. Timofeeva
Russian Federation
References
1. Troyanov St., Wall C.A., Miller J.A., et al. Focal and segmental glomerulosclerosis: definition and relevance of a partial remission. J. Am. Soc. Nephrol. 2005; 16: 1061–1068.
2. Braden G.L., Mulhern J.G., O'Shea M.H. et al. Changing incidence of glomerular diseases in adults. Am. J. Kidney Dis. 2000; 35 (5): 878–883.
3. Ichikawa I., Fogo A. Focal segmental glomerulosclerosis. Pediatr. Nephrol. 1996; 10 (3): 347–391.
4. Korbet S.M. Treatment of primary focal segmental glomerulosclerosis. J. Am. Soc. Nephrol. 2002; 62: 2301–2310.
5. Lieberman K.V., Tejani A. A randomized double-blind placebo-controlled trial of cyclosporine in steroid-resistant focal segmental glomerulosclerosis in children. J. Am. Soc. Nephrol. 1996; 7 (1): 56–63.
6. Ehrich J.H., Pape L., Schiffer M. Corticosteroid-resistant nephrotic syndrome with focal and segmental glomerulosclerosis: an update of treatment options for children. Paediatr. Drugs. 2008; 10 (1): 9–22.
7. Rydel J.J., Korbet S.M., Borok R.Z., Schwartz M.M. Focal segmental glomerular sclerosis in adults: Presentation, course, and response to treatment. Am. J. Kidney Dis. 1995; 25: 534.
8. Meyrier A., Simon P., Perret G., Condamin-Meyrier M.C. Remission of idiopathic nephrotic syndrome after treatment with cyclosporine. Ann. Br. Med. J. 1986; 292: 789–792.
9. Suthanthiran M., Strom T.B. Immunoregulatory drugs: mechanistic basis for use in organ transplantation. Pediatr. Nephrol. 1997. 11(5): 651–657.
10. Scheinman R.I., Cogswell P.G., Lofquist A.K., Baldwin A.S. Role of transcription activation of Iβα in mediation of immunosupression by glucocorticoids. Sience. 1995; 270: 283–286.
11. Tune B.M., Mendoza S.A. Treatment of the idiopathic nephrotic syndrome: regimens and outcomes in children and adults. J. Am. Soc. Nephrol. 2001; 12: 44–47.
12. Комарова О.В., Цыгин А.Н., Леонова Л.В. и др. Терапия циклосоприном А у детей с фокальносегментарным гломерулосклерозом. Вопросы современной терапии. 2009; 8(5): 93–97.
13. Joshua Y., Kausma A., Kitching R. A New approach to idiopathic nephrotic syndrome. J. Am. Soc. Nephrol. 2007; 18: 2621–2622.
14. Klein M., Radhakrishnan J., Appel G. Cyclosporine treatment of glomerular diseases. Ann. Rev. Med. 1999; 50: 1–15.
15. Цыгин А.Н., Комарова О.В., Сергеева Т.В. и др. Нефротический синдром. Клинические рекомендации по педиатрии. Под ред. А.А. Баранова. М.: Геотар–Медиа. 2005; 107-128.
16. Kveder R. Therapy-resistant focal and segmental glomerulosclerosis. Nephrol. Dial. Transplant. 2003; 18 (Suppl. 5): 34–37.
17. Niaudet P. Treatment of childhood steroid resistant idiopathic nephrosis with a combination of cyclosporine and prednisone. French Society of Pediatric Nephrology. J. Pediatr. 1994; 125 (6): 981–986.
18. Waldo F.B., Benfield M.R., Kohaut E.C. Therapy of focal and segmental glomerulosclerosis with methylprednisolone, cyclosporine A, and prednisone. Pediatr. Nephrol. 2009; 12(5): 397–400.
19. Burgess E. Management of focal segmental glomerulosclerosis: evidence-based recommendations. Kidney Int. Suppl. 1999; 70: 26–32.
20. El-Husseini A., El-Basuony F., Mahmoud I. et al. Long-term effects of cyclosporine in children with idiopathic nephrotic syndrome: a single-centre experience. Nephrol. Dial. Transplant. 2005; 20(11): 2433–2438.
21. Meyrier A., Noel L.H., Auriche P., Callard P. Long-term renal tolerance of cyclosporin A treatment in adult idiopathic nephrotic syndrome. Collaborative Group of the Societe de Nephrologie. Kidney Int. 1994; 45 (5): 1446–1456.
Review
For citations:
Komarova O., Matveeva M., Tsygin A., Leonova L., Timofeeva A. EFFICACY AND SAFETY OF PROLONGED TREATMENT WITH CYCLOSPORINE IN CHILDREN WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS. Current Pediatrics. 2010;9(4):155-159.