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CHRONIC FUNCTIONAL CONSTIPATION IN CHILDREN — FROM UNDERSTANDING THE PROBLEM TO THE PROPER TREATMENT

Abstract

Functional origin is known in 95% of children with constipation. According to ICD-10 there is traditional distinction between syndrome of irritated bowel and proper functional constipation which have wide spectrum of causes. Rome criteria III propose initial diagnostic criteria of these disorders but the use of the criteria in pediatrics is frequently complicated. Clinical practice of pediatrician demands differentiation of constipations into hypertonic and hypotonic ones. Treatment programs include necessary component — laxative drugs which are useful in cases of subcompensated and decompensated types of constipation. One of the laxative drugs is Forlax containing polyethyleneglycol 4.000; it can be given to children 6 months old and older. The literature data shows high efficiency and safety of the drug.
Key words: children, constipation, laxative drugs.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(6):69-77)

About the Authors

V.F. Privorotskiy
Children’s Consultative Diagnostic Center, St.-Petersburg
Russian Federation




N.E. Luppova
Medical Academy of Postgraduate Education, St.-Petersburg
Russian Federation


References

1. Александрова В.А. Диагностика и лечение запоров у детей. СПб.: МАПО. 2004. 24 с.

2. Бельмер С.В., Гасилина Т.В., Хавкин А.И., Эйберман А.С. Функциональные нарушения органов пищеварения у детей. М. 2006. 44 с.

3. Хавкин А.И. Хронические запоры. Подход к терапии. Русский медицинский журнал. 2006; 3: 3–6.

4. Гасилина Т., Бельмер С. Функциональный запор у детей: проблемы определения, диагностики и лечения. Врач. 2009; 8: 10–14.

5. Эрдес С.И. Запоры у детей. Фарматека. 2007; 13: 47–52.

6. Pediatric Gastrointestinal Disease (Pathophysiology, Diagnosis, Management). Еd. R.Wyllie, J.S. Hyams. Philadelphia. 1999. Р. 271–550.

7. Хавкин А.И. Функциональные нарушения желудочно-кишечного тракта у детей раннего возраста. М. 2000. 72 с.

8. Хавкин А.И., Бабаян М.Л. Лечение хронических запоров (клиника, диагностика, лечение). М.: НИИ педиатрии и детской хирургии. 2005. 30 с.

9. Pediatric Gastrointestinal Motility Disorders. Еd. P.E. Hyman. NY. 1994. Р. 129–145.

10. Захарова И.Н. Функциональные запоры у детей. Русский медицинский журнал. 2009; 15: 988–996.

11. Практическое руководство по детским болезням. Под ред. В.Ф. Коноплиной, А.Г. Румянцева, С.В. Бельмера, А.И. Хавкина. М.: Медпрактика–М. 2003. С. 249–266.

12. Evaluation and treatment of constipation in infants and children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. JPGN. 2006; 43 (1): 1–13.

13. Хавкин А.И. Микрофлора пищеварительного тракта. М. 2006. С. 171 – 374.

14. Запруднов А.М., Царькова О.Н., Харитонова Л.А. Функциональные расстройства кишечника и хронические запоры у детей. Вопросы детской диетологии. 2010; 1: 66 –81.

15. Nelson Textbook of Pediatrics (17th еd.). Philadelphia. 2004. Р. 1101–1187.

16. Кущ Н.Л. Запоры у детей. Киев. 1976. 176 с.

17. Спиваковский Ю.М., Шульгина Е.Н., Эйберман А.С. Синдром раздраженного кишечника у детей в свете «Римских критериев III» и роль иммуномодулирующей терапии в коррекции основных проявлений болезни. Русский медицинский журнал. 2010; 5: 255–260.

18. Drossman D.A. The functional gastrointestinal disorders and the Rome III process. Gastroenterol. 2006; 130: 1377–1390.

19. Thompson W.G. The road to Rome. Gastroenterol. 2006; 130: 1552–1556.

20. Loening-Baucke V. Chronic constipation in children. Gastroenterol. 1993; 105: 1557–1564.

21. Loening-Baucke V. Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation in childhood. Pediatrics. 1997; 100: 228–232.

22. Шульпекова Ю.О. Принципы лечения запора. Русский медицинский журнал. 2010; 13: 854–858.

23. Корниенко Е.А. Лечение хронического запора у детей. Вопросы современной педиатрии. 2010; 9 (2): 136–140.

24. Candy D., Belsy J. Macrogol (polyethylene glycol) laxatives in childrenwith functional constipation and faecal impaction: a systematic review. Arch. Dis. Child. 2009; 94: 156–160.

25. Dupont Ch., Leluyer B., Maamri N. Double-blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lactulose in constipated children. J. Pediatr. Gastroenterol. Nutr. 2005; 41: 625–633.

26. Dupont Ch., Leluyer B., Amar F. et al. A Dose determination study of polyethylene glycol 4000 in constipated children: factors influencing the maintenance dose. J. Pediatr. Gastroenterol. Nutr. 2006; 42(2): 178–185.

27. Wang B.X., Wang M.G., Jiang M.Z. et al. Forlax in the treatment of childhood constipation: a randomized, controlled, multicentre clinical study (in Chinese). Zhongguo Dang Dai Er Ke Za Zhi. 2007; 9: 429–432.

28. Couturier D., Licht H.A. Comparative study of the efficacy of Forlax versus Lactulose in the treatment of the functional constipation in adult patients. Abstract Gastro. 1996; 104: 3.

29. Denis Ph., Teilet L., Moulias R.L. et al. Tolerance and efficacy of forlax comparative long-term study versus lactulose in patients with functional constipation. Mensuel des maladies de l’appareil digestive, du foie, des voies biliaires et de la nutrition. 1996; 10 (2): 8.


Review

For citations:


Privorotskiy V., Luppova N. CHRONIC FUNCTIONAL CONSTIPATION IN CHILDREN — FROM UNDERSTANDING THE PROBLEM TO THE PROPER TREATMENT. Current Pediatrics. 2010;9(6):69-77.

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