Preview

Current Pediatrics

Advanced search

INHALATION THERAPY IN CHILDREN: ISSUES AND OPTIONS

https://doi.org/10.15690/vsp.v13i2.977

Abstract

Today inhalation therapy forms the basis of treatment for children and adults with bronchial asthma. In the current market there is a great number of various drug delivery systems, such as: nebulisers, pressurised metered-dose inhalers and dry powder inhalers. Guidelines for diagnosis and management of bronchial asthma present preferred and alternative devices for treatment of children in their age group. Although choosing an inhaler device one should consider not only age and cognitive peculiarities in each patient, but also his individual preferences. Poor compliance with treatment in bronchial asthma is often due to the fact that a patient experiences problems using a dosage device. Though it is known that the effective inhalation therapy is achieved by following correct inhalation techniques given in guidelines to the concrete device. Incorrect inhaler use causes loss of asthma control. Meanwhile just one half of patients can use the medication correctly after self-studying of guidelines. Consequently, a physician should train a patient to use the device and control his actions. Up-to-date delivery systems for inhalation therapy and principles of their selection in children’s treatment are considered in the article. The survey of research data concerning the use of dry powder inhaler type-easyhaler is presented as well.

About the Authors

L. R. Selimzyanova
Scientific Center of Children’s Health, Moscow; I.M. Sechenov First Moscow State Medical University
Russian Federation
Liliya Selimzyanova, Candidate of Medical Science, chief research scientist of the department of standardization and clinical pharmacology of Scientific Center of Children’s Health, assistant of a chair of pediatrics and child’s rheumatology of the I.M. Sechenov First Moscow State Medical University


E. А. Promyslova
Scientific Center of Children’s Health, Moscow
Russian Federation


E. А. Vishnyeva
Scientific Center of Children’s Health, Moscow
Russian Federation


References

1. Sinopal'nikov A. I., Klyachkina I. L. Rossiiskie meditsinskie vesti — Russian Medical News. 2003; 1 (8): 2–7.

2. Niven R. W., Ip A. Y., Mittleman S., Prestrelski S. J., Arakawa T. Pharm. Res. 1995; 12 (1): 53–59.

3. Munster A. M., Benstrup E., Jensen J. I., Gram J. J. Aerosol. Med. 2000; 13 (4): 325–333.

4. Simonova O. I., Lukina O. F. Voprosi sovremennoi pediatrii — Current Pediatrics. 2012; 11 (2): 132–139.

5. Nikander K., Turpeinen M., Wollmer P. J. Aerosol. Med. 1999; 12 (2): 47–53.

6. From the Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA). 2012. Available from: http://www.ginasthma.org/

7. From the Global Strategy for the Diagnosis and Management of Asthma in Children 5 Years and Younger, Global Initiative for Asthma (GINA). 2009. Available from: http://www.ginasthma.org/

8. Allergologiya i immunologiya [Allergology and Immunology]. Ed. Baranov A. A., Khaitov R. M. М. 2011. 256 p.

9. Klinicheskaya allergologiya detskogo vozrasta s neotlozhnymi sostoyaniyami. Rukovodstvo dlya vrachey [Infant Clinical Allergology With Medical Emergencies. Guidance for Doctors]. Ed. Balabolkin I. I., Bulgakova V. A. М. 2011. 264 p.

10. From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD). 2014. Available from: http://www.goldcopd.org/

11. Brocklebank D., Ram F., Wright J., Barry P., Cates C., Davies L., Douglas G., Muers M., Smith D., White J. Health Technol Assess. 2001; 5 (26): 1–149.

12. Dolovich M. B., Ahrens R. C., Hess D. R., Anderson P., Dhand R., Rau J. L., Smaldone G. C., Guyatt G. Chest. 2005; 127 (1): 335–371.

13. Thompson J., Irvine T., Grathwohl K., Roth B. Misuse of metereddose inhalers in hospitalized patients. Chest. 1994 105 (3): 715–717.

14. Molimard M., Raherison C., Lignot M., Depont F., Abouelfath A., Moore N. J. Aerosol. Med. 2003; 16 (3): 249–254.

15. Lavorini F., Magnan A., Dubus J. C., Voshaar T., Corbetta L., Broeders M., Dekhuijzen R., Sanchis J., Viejo J. L., Barnes P., Corrigan C., Levy M., Crompton G. K. Respir. Med. 2008; 102 (4): 593–604.

16. Rootmensen G. N., van Keimpema A. R., Looysen E. E., van der Schaaf L., Jansen H. M., de Haan R. J. J. Aerosol. Med. 2007; 20 (4): 429–433.

17. Vishneva Ye. A., Namazova-Baranova L. S., Alekseyeva A. A., Efen diyeva K.Ye., Levina Yu. G., Voznesenskaya N. I., Tomi lo va A.Yu., Selimzyanova L. R., Promyslova Ye. A. Pediatri cheskaja far ma ko logija — Pediatric pharmacology. 2013; 10 (4): 60–72.

18. Ronmark E., Jogi R., Lindqvist A., Haugen T., Meren M., Loit H. M., Sairanen U., Sandahl A., Lundback B. J. Asthma. 2005; 42 (3): 173–178.

19. Crompton G. K., Barnes P. J., Broeders M., Corrigan C., Corbetta L., Dekhuijzen R., Dubus J. C., Magnan A., Massone F., Sanchis J., Viejo J. L., Voshaar T. Respir. Med. 2006; 100 (9): 1479–1494.

20. Giraud V., Roche N. Eur. Respir. J. 2002; 19 (2): 246–251.

21. Chrystyn H., Price D. Prim. Care. Respir. J. 2009; 18 (4): 243–249.

22. Akdis C. A., Agache I. Global Atlas of asthma. Eur. Acad. Allergy & Clin. Immunol. 2013. www.eaaci.org

23. Laube B. L., Janssens H. M., de Jongh F. H. C., Devadason S. G., Dhand R., Diot P., Everard M. L., Horvath I., Navalesi P., Voshaar T., Chrystyn H. Eur. Respir. J. 2011; 37 (6): 1308–1417.

24. Labiris N. R., Dolovich M. B. Brit. J. Clin. Pharmacol. 2003; 56 (6): 588–599.

25. Williamson I. J., Matusiewicz S. P., Brown P. H., Greening A. P., Crompton G. K. Eur. Respir. J. 1995; 8 (4): 590–592.

26. Usmani O. S., Biddiscombe M. F., Barnes P. J. Am. J. Respir. Crit. Care Med. 2005; 172 (12): 1497–1504.

27. Gerritsen J., Rottier B. Paediatric Asthma. K.-H. Carlsen, J. Gerritsen (eds). Eur. Respir. Soc. Monographs. 2012; 17 (56): 199–209.

28. Pedersen S., Hansen O. R., Fuglsang G. Arch. Dis. Child. 1990; 65 (3): 308–310.

29. Poukkula A., Alanko K., Kilpio K., Knuuttila A., Koskinen S., Laitinen J., Lehtonen K., Liippo K., Lindqvist A., Lahelma S., Paananen M., Ruotsalainen E. M., Salomaa E. R., Silvasti M., Suuronen U., Toivanen P., Vilkka V. Clin. Drug Investig. 1998; 16 (2): 101–110.

30. Tukiainen H., Rytila P., Hamalainen K. M., Silvasti M. S., KeskiKarhu J. Respir. Med. 2002; 96 (4): 221–229. 31. Ahonen A., Leinonen M., Ranki-Pesonen M. Curr. Ther. Res. 2000; 61 (2): 61–73.

31. Vanto T., Hamalainen K. M., Vahteristo M., Wille S., Nja F., Hyldebrandt N. J. Aerosol. Med. 2004; 17 (1): 15–24.

32. Galffy G., Mezei G., Nemeth G., Tamasi L., Muller V., Selroos O., Orosz M. Drugs R D. 2013; 13 (3): 215–222.

33. Thomas V., Burden A., von Ziegenweidt J., Gould S., Hutton C. Eur. Respir. J. 2013; 42 (57): 3833.


Review

For citations:


Selimzyanova L.R., Promyslova E.А., Vishnyeva E.А. INHALATION THERAPY IN CHILDREN: ISSUES AND OPTIONS. Current Pediatrics. 2014;13(2):89-94. (In Russ.) https://doi.org/10.15690/vsp.v13i2.977

Views: 1007


ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)