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Sensitive Skin Syndrome in Children with Atopic Dermatitis: Pathogenesis and Management Features

https://doi.org/10.15690/vsp.v18i4.2046

Abstract

The atopic dermatitis (AD) is common skin disease and has significant impact on patients and their families quality of life. In recent years the term “sensitive skin" has been used more frequently. It is separate syndrome with subjective perception (such as burning, itching, tingling, etc.) along with thickening and dryness of the skin in response to environmental factors (biotic, abiotic and anthropogenic) which normally do not cause such symptoms. This syndrome is often associated with AD. The AD and sensitive skin syndrome pathogenesis and their management are presented in the article. Efficiency and safety parameters of pimecrolimus 1% cream in children (including its appliance on sensitive skin areas) are analysed.

About the Authors

Nikolay N. Murashkin
National Medical Research Center of Children's Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs
Russian Federation

Receiving research grants from pharmaceutical companies Jansen, Eli Lilly, Novartis. Scientific consultant of Galderna, Pierre Fabre, Bayer, Leofarma, Pfizer, AbbVie, Amryt Pharma, Zeldis Pharma LLC companies


Disclosure of interest:

Absence of a reportable conflict of interests



Roman V. Epishev
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Scientific consultant of Eli Lilly, Novartis, AbbVie, Amryt Pharma companies



Dmitri V. Fedorov
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Absence of a reportable conflict of interests



Alexander I. Materikin
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Scientific consultant of Eli Lilly, Novartis, AbbVie, Amryt Pharma companies



Eduard T. Ambarchyan
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Scientific consultant of Eli Lilly, Novartis, AbbVie, Amryt Pharma, Jansen companies



Leonid A. Opryatin
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Absence of a reportable conflict of interests



Alena A. Savelova
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Absence of a reportable conflict of interests



Roman A. Ivanov
National Medical Research Center of Children's Health
Russian Federation

Moscow


Disclosure of interest:

Absence of a reportable conflict of interests



Wasel Ahmad
Berbekova Kabardino-Balkarian State University
Russian Federation

Republic of Kabardino-Balkaria


Disclosure of interest: Absence of a reportable conflict of interests


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Review

For citations:


Murashkin N.N., Epishev R.V., Fedorov D.V., Materikin A.I., Ambarchyan E.T., Opryatin L.A., Savelova A.A., Ivanov R.A., Ahmad W. Sensitive Skin Syndrome in Children with Atopic Dermatitis: Pathogenesis and Management Features. Current Pediatrics. 2019;18(4):285-293. (In Russ.) https://doi.org/10.15690/vsp.v18i4.2046

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