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Efficacy and Safety of Peptide Vaccine in Prevention of SARS-CoV-2 Infection: Prospective Study among Healthcare Professionals

https://doi.org/10.15690/vsp.v21i2.2386

Abstract

The pandemic caused by the new coronavirus infection remains the topical health issue and constitutes serious threat to the entire world. Nowadays, active immunization against new type of coronavirus infection continues in Russian Federation and in all other countries. Vaccination is the crucial component in comprehensive program for COVID-19 prevention and control. Mass immunization of population can prevent both admissions and hospitalization in conditions of high incidence of COVID-19 and thereby reduce the burden on the health system. Despite the remaining complications in combating the SARS-CoV-2 pandemic, preventive vaccination is by far the most effective method for protection against this infection Clinical studies on the efficacy of various preventive vaccinations in different regions of the world are extremely relevant especially under conditions of the emergency use authorization for vaccines against new coronavirus infection, the changing epidemiological situation, and the wide variability of different types of vaccines. All countries will need continuously updated data on vaccine efficacy to address new challenges such as weakening post-vaccine protection, new SARS-CoV-2 strains, and need for other preventive measures to mitigate the pandemic.

About the Authors

Leyla S. Namazova-Baranova
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University; Belgorod National Research University
Russian Federation

Moscow; Belgorod


Disclosure of interest:

Not declared.



Marina V. Fedoseenko
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Firuza Ch. Shakhtakhtinskaya
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Tatiana A. Kaliuzhnaia
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Margarita A. Soloshenko
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Svetlana V. Tolstova
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Arevaluis M. Selvyan
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Tatiana E. Privalova
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”; Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Snezhana D. Timoshkova
Pirogov Russian National Research Medical University
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Albina A. Melnikova
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Aleksandr V. Gorelov
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Antonina A. Ploskireva
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Ilina Z. Mustafina
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Elena V. Melekhina
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Denis V. Usenko
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Zhanna B. Ponezheva
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



Khadizhat G. Omarova
Central Research Institute of Epidemiology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Moscow


Disclosure of interest:

Not declared.



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Review

For citations:


Namazova-Baranova L.S., Fedoseenko M.V., Shakhtakhtinskaya F.Ch., Kaliuzhnaia T.A., Soloshenko M.A., Tolstova S.V., Selvyan A.M., Privalova T.E., Timoshkova S.D., Melnikova A.A., Gorelov A.V., Ploskireva A.A., Mustafina I.Z., Melekhina E.V., Usenko D.V., Ponezheva Zh.B., Omarova Kh.G. Efficacy and Safety of Peptide Vaccine in Prevention of SARS-CoV-2 Infection: Prospective Study among Healthcare Professionals. Current Pediatrics. 2022;21(2):83-94. (In Russ.) https://doi.org/10.15690/vsp.v21i2.2386

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