Вопросы современной педиатрии

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Особенности клинических фенотипов пищевой аллергии при синдроме перекрестной реактивности

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В последние годы особое внимание уделяют изучению такого иммуногенного феномена, как синдром перекрестной сенсибилизации. Доказано, что зачастую клинические проявления пищевой аллергии у пациентов не связаны с продуктом питания, а обусловлены сенсибилизацией к пыльце растений. Возможности современной диагностики позволяют не только определять тип сенсибилизации, но и идентифицировать «виновный» белок аллергена-триггера. В статье рассмотрены возможные клинические проявления пищевой аллергии, обусловленные перекрестными реакциями как между родственными, так и между таксономически не связанными аллергенами. Дан алгоритм прогнозирования степени тяжести клинических реакций, а также представлен перечень белков, участвующих в реакциях перекреста.

Об авторах

Т. А. Евдокимова
Сибирский государственный медицинский университет, Томск

Ф. И. Петровский
Ханты-Мансийская государственная медицинская академия

Л. М. Огородова
Сибирский государственный медицинский университет, Томск

М. М. Федотова
Сибирский государственный медицинский университет, Томск

О. С. Федорова
Сибирский государственный медицинский университет, Томск

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Для цитирования:

Евдокимова Т.А., Петровский Ф.И., Огородова Л.М., Федотова М.М., Федорова О.С. Особенности клинических фенотипов пищевой аллергии при синдроме перекрестной реактивности. Вопросы современной педиатрии. 2013;12(2):6-11.

For citation:

Evdokimova T.A., Petrovskii F.I., Ogorodnova L.M., Fedotova M.M., Fedorova O.S. Features of Clinical Phenotypes of Food Allergy Syndrome of Cross-reactivity. Current Pediatrics. 2013;12(2):6-11. (In Russ.)

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