Functional Constipation in Children: Chronic Disease or Developmental Problem?
https://doi.org/10.15690/vsp.v12i2.622
Abstract
This article reviews current perspectives on a serious issue of pediatrics — constipation in children. Lacking most of the organic causes for the formation of constipation with delayed treatment is likely to disrupt the quality of life and hard correctable complications. Modern treatment in childhood constipation should combine drug and non-drug methods, the most child-friendly, while the commonly used rectal treatments should be tightly restricted.
About the Authors
V. N. Panfilova
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Children Hospital
Russian Federation
Contacts: Panfilova Victoria Nikolayevna, PhD, MD, associate professor of Chair of Pediatrics, Institute of Postgraduate Education, State Budget Educational Institution of High Professional Education “Professor V.F. Voyno-Yasenetskiy Krasnoyarsk State Medical University”, Ministry of Health, Russian Federation; chief children’s specialist-gastroenterologist, Ministry of Health, Krasnoyarsk Region Address: 660074, Krasnoyarsk, Academician Kirenskiy str. 2A, Tel.: (391) 243-55-82, e-mail: vpanfiloff@mail.ru
Russian Federation
Contacts: Panfilova Victoria Nikolayevna, PhD, MD, associate professor of Chair of Pediatrics, Institute of Postgraduate Education, State Budget Educational Institution of High Professional Education “Professor V.F. Voyno-Yasenetskiy Krasnoyarsk State Medical University”, Ministry of Health, Russian Federation; chief children’s specialist-gastroenterologist, Ministry of Health, Krasnoyarsk Region Address: 660074, Krasnoyarsk, Academician Kirenskiy str. 2A, Tel.: (391) 243-55-82, e-mail: vpanfiloff@mail.ru
S. N. Doroshchenko
Krasnoyarsk Regional Clinical Children Hospital
Russian Federation
Russian Federation
T. V. Tret’yakova
Krasnoyarsk Regional Clinical Children Hospital
Russian Federation
Russian Federation
References
1. Youssef N. N., Langseder A. L., Verga B. J., Mones R. L., Rosh J. R. Chronic childhood constipation is associated with impaired quality of life: a case-controlled study. J. Pediatr. Gastroenterol. Nutr. 2005; 41 (1): 56–60.
2. NICE. Constipation in children and young people. CG99. NICE, London. 2010. Available from http://guidance.nice.org.uk/CG99
3. Hyman P. E., Milla P. J., Benninga M. A., Davidson G. P., Fleisher D. F., Taminiau J. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology. 2006; 30: 1519–1526.
4. Rasquin A., Lorenzo C., Di Forbes D., Guiraldes E., Hyams J. S., Staiano A., Walker L. S. Childhood functional gastrointestinal disor ders: child/adolescent. Gastroenterology. 2006; 130: 1527–1537.
5. Hyams J. S., Treem W. R., Etienne N. L., Weinerman H., MacGilpin D., Hine P., Choy K., Burke G. Effect of infant formula on stool characteristics of young infants. Pediatr. 1995; 95: 50–54.
6. Fontana M., Bianch C., Cataldo F., Conti Nibali S., Cucchiara S., Gobio Casali L., Iacono G., Sanfilippo M., Torre G. Bowel frequency in healthy children. Acta Paediatr. Scand. 1987; 78: 682–684.
7. Baker S. S. et al. Evoluation and treatment of constipation in infants and children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Clinical Practice Guideline. JPGN/Lippincott Williams & Wilkins, Philadelphia. 2006; 43: 1–13.
8. Hyman P. E., Fleisher D. Functional fecal retention. Pract. Gastroenterol. 1992; 31: 29–37.
9. Pykov M. I., Mazankova L. N., Ovechkina N. R. Ultrasonic diagnostics of inflammatory changes of large intestine in children. Coloproctology. 2007; 1 (19): 27–31.
10. Bijos A., Czerwionka-Szaflarska M., Mazur A., Romanczuk W. The usefulness of ultrasound examination of the bowel as a method of assessment of functional chronic constipation in children. Pediatr. Radiology. 2007; 37 (12): 1247–1252.
11. Darge K., Anupindi S., Keener H., Rompel O. Ultrasound of the bowel in children: how we do it. Pediatr. Radiology. 2010; 40:4: 528–536.
12. Dvoryakovskiy I. V., Lukin V. V., Kostylyov F. A. Dynamics of rectum wall changes according to echography and Dopplerographia analysis in children with chronic constipation. SonoAce-Ultrasound. 2003; 11: 79–83.
13. Candy D. C., Edwards D., Geraint M. Treatment of faecal impaction with polyethelene glycol plus electrolytes (PGE + E) followed by a double-blind comparison of PEG + E versus lactulose as maintenance therapy. JPGN. 2006; 43 (1): 65–70.
14. Dupont C., Leluyer B., Maamri N., Morali A., Joye J.-P., Fiorini J.-M., Abdelatif A., Baranes C., Benoit S., Benssoussan A., Boussioux J., Boyer P., Brunet E., Delorme J., Francois-Cecchin S., Gottrand F., Grassart M., Hadji S., Kalidjian A., Languepin J., Leissler C., Lejay D., Livon D., Lopez J., Mougenot J., Risse J., Rizk C., Roumaneix D., Schirrer J., Thoron B., Kalach N. Double-blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lactulose in constipated children. JPGN. 2005; 41 (5): 625–633.
15. Loening-Baucke V., Pashankar D. S. A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence. Pediatrics. 2006; 118 (2): 528–535.
16. Thomson M. A., Jenkins H. R., Bisset W. M., Heuschkel R., Kalra D. S., Green M. R., Wilson D. C., Geraint M. Polyethylene glycol 3350 plus electrolytes for chronic constipation in children: a double blind, placebo controlled, crossover study. Arch. Dis. Child. 2007; 92 (11): 996–1000.
17. Nurko S., Youssef N. N., Sabri M., Langseder A., McGowan J., Cleveland M., Di Lorenzo C. PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial. J. Pediatr. 2008; 153 (2): 254–261.
18. Perkin J. M. Constipation in childhood: a controlled comparison between lactulose and standardized senna. Curr. Med. Res. Opin. 1977; 4 (8): 540–543.
19. Romanczuk W., Korczowski R. Duphalac (lactulose) in the treatment of chronic constipation in children. Wiad Lek. 1995; 48 (1–12): 96–99.
20. Connolly P., Hughes I. W., Ryan G. Comparison of «Duphalac» and «irritant» laxatives during and after treatment of chronic constipation: a preliminary study. Curr. Med. Res. Opin. 1974–1975; 2 (10): 620–625. 21. Tabbers M. M., Boluyt N., Berger M. Y., Benninga M. A. Constipation in children. Clin. Evid. (Online). 2010: 0303. PMCID: PMC2907595.
21. Rogers J. Reducing the misery of constipation in children. Pract. Nursing. 2005; 1 (1): 12–16.
22. Afzal N. A., Tighe M. P., Thomson M. A. Constipation in children. Italian J. Pediatr. 2011; 37: 28. Doi: 10.1186/1824-7288-37-28.
23. Hillemeier C. An overview of the effects of dietary fiber on gastrointestinal transit. Pediatrics. 1995; 96 (5 Pt. 2): 997–999.
24. Guimaraes E.V., Goulart E.M., Penna F. J. Dietary fiber intake, stool frequency and colonic transit time in chronic functional constipation in children. Braz. J. Med. Biol. 2001; 34 (9): 1147–1153.
25. El-Hodhod M. A., Younis N. T., Zaitoun Y. A., Daoud S. D. Cow's milk allergy related pediatric constipation: appropriate time of milk tolerance. Pediatr. Allergy Immunol. 2010; 21 (2 Pt. 2): 7–12.
26. Silva D., Soraia T., Dirceu S., Naspitz C. K., DaSilva P., Francy R., Neto U. F., MeMorais M. B. Cow's milk protein intolerance and chronic constipation in children. Pediatr. Allergy Immunol. 2001; 12 (339): 42.
27. Andiran F., Dayi S., Mete E. Cow’s milk consumption in constipation and anal fissure in infants and young children. J. Paediatr. Child Health. 2003; 39 (329): 31.
28. Tsymbalova Ye. G., Potapov A. S., Baranov K. N. Chronic constipation in children. Voprosi sovremennoi pediatrii — Current Pediatrics. 2002; 1 (6): 56–61.
29. Banaszkiewicz A., Szajewska H. Ineffectiveness of Lactobacillus GG as an adjunct to lactulose for the treatment of constipation in children: a double-blind, placebo-controlled randomized trial. J. Pediatr. 2005; 146 (3): 364–369.
Review
For citations:
Panfilova V.N., Doroshchenko S.N., Tret’yakova T.V. Functional Constipation in Children: Chronic Disease or Developmental Problem? Current Pediatrics. 2013;12(2):66-71. (In Russ.) https://doi.org/10.15690/vsp.v12i2.622
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