ЧАСТО БОЛЕЮЩИЕ ДЕТИ: ЧТО ЕЩЕ КРОМЕ ИНФЕКЦИЙ?
https://doi.org/10.15690/vsp.v12i1.560
Аннотация
В обзоре данных литературы и собственных клинических наблюдений представлена оригинальная концепция дифференциальной диагностики состояний, объединяемых практическими врачами в понятие «часто болеющие дети». Группа диспансерного наблюдения «часто болеющие дети» определена как гетерогенная на основании сведений о высокой (20–40%) частоте атопических (аллергический ринит, бронхиальная астма) заболеваний и вариабельной частоты первичных иммунодефицитов. Предложены простые дифференциально-диагностические признаки и схема сбора анамнеза у часто болеющих детей, позволяющие своевременно установить диагноз аллергического заболевания, первичного иммунодефицита. Дана характеристика рецидивирующих респираторных инфекций. Детально описаны онтогенетические и конституциональные предпосылки и механизмы развития рецидивирующих респираторных инфекций в детском возрасте. Лечебные и профилактические вмешательства обоснованы с учетом группы часто болеющих детей и гетерогенности причин рецидивирующих респираторных инфекций.
Об авторах
Д. Ю. Овсянников
Российский университет дружбы народов, Москва
Россия
Ovsyannikov Dmitriy Yuryevich, PhD, Head of Chair of Pediatrics, Federal State Budget Educational Institution of High Professional Education “People’s Friendship University of Russia” Address: 117198, Moscow, Miklukho-Maklaya str., 6, Tel.: (499) 154-44-59, e-mail: mdovsyannikov@yahoo.com
Россия
Ovsyannikov Dmitriy Yuryevich, PhD, Head of Chair of Pediatrics, Federal State Budget Educational Institution of High Professional Education “People’s Friendship University of Russia” Address: 117198, Moscow, Miklukho-Maklaya str., 6, Tel.: (499) 154-44-59, e-mail: mdovsyannikov@yahoo.com
Т. Ю. Илларионова
Российский университет дружбы народов, Москва,
Россия
Россия
Л. В. Пушко
Российский университет дружбы народов, Москва
Россия
Россия
Л. Г. Кузьменко
Российский университет дружбы народов, Москва
Россия
Россия
Список литературы
1. Bredy M. Respiratory viral infections. Infectious diseases. Edited by D. Marry. Moscow: Praktika. 2006. Pp. 604–630.
2. Acute respiratory diseases in children: treatment and prophylaxis. Textbook for doctors. Moscow: Publishing house of Union of Pediatricians of Russia. 2002. 73 pp.
3. Samsygina G. A. Frequently ailing children: problems of pathogenesis, diagnostics and treatment. Consilium medicum. 2004; 6 (2): pp. 3–8.
4. Bartlett J. G. Management of respiratory tract infection. 3rd Ed. Philadelphia. 2001. Р. 178–182.
5. Albitskiy V.Yu., Baranov A. A., Kamayev I. A. Frequently ailing children. Nizhniy Novgorod: Publishing house NizhGMA. 2003. 174 pp.
6. Romagani S. Th1/Th2 paradigm. Immunology Today. 1997; 18 (6): 263–266.
7. Martinez F. D. Role of viral infections in the inception of astma and allergies during childhood: could they be protective? Thorax. 1994; 49: 1189.
8. von Mutius E., Martinez F. D., Fritzch C. et al. Prevalence of asthma and atopy in two areas of West and East Germany. Am. J. Respir. Crit. Care Med. 1994; 149: 358.
9. Strachan D. P. Hay fever, hygiene, and household size. BMJ. 1989; 299 (6710): 1259–1260.
10. Lauener R. P. Allergien: Genetisch determiniertes Schicksal oder durch Umwelteinflusse bestimmte Krankheit? Die Ontogenese der Immun-Kompetenz und Allergie-Entstehung. Monatsschrft Kinderheilkunde. 2003; 1: 63–67.
11. Veraksa A., Del Campo M., Mc Ginnis W. Developmental patterning genes and their conserved functions: from model organisms to humans. Mol. Genet. Metab. 2000; 69: 85–100.
12. Zaplatnikov A. L., Korovina N. A., Girina A. A. et al. Prophylaxis of recurrent respiratory diseases in frequently ailing children. Questions of practical Pediatrics. 2010; 5 (6): pp. 55–60.
13. Zinovyeva N. V., Davydova N. V., Shcherbina A.Yu. et al. Frequently ailing children: mythes and reality. Allergology and immunology in Pediatrics. 2005; 1 (4): pp. 26–30.
14. Sokolova T. S. Bronchial asthma in children. Particular allergology. Edited by A. D. Ado. Moscow: Medicine. 1976. Pp. 261–290.
15. Wright A. L., Taussing L. M., Ray C. G. et al. The Tucson Children’s Respiratory Study II: Lower respiratory tract illness in the first year of life. Am. J. Epidemiol. 1989; 129: 1232.
16. Milne A. A. Sneezles. Now we are six. N.-Y: E. P. Dutton and Co. 1927.
17. Yakovleva N. V. Respiratory viruses. Mechanisms of inflammation in bronches and lungs ad anti-inflammatory treatment. Edited by G. B. Fedoseyev. St.-Petersburg.: Normed-Izdat. 1998. Pp. 25–66.
18. Smolenov I. V. Asthma and sibilant rales induced by viral infection. Consilium Medicum. Appendix. “Bronchial asthma, allergic rhinitis and conjunctivitis”. Clinical recommendations. Edited by Chuchalin A. G. 2001. Pp. 9–14.
19. Soldatov D. G. Virus-induced bronchial asthma. Bronchial asthma. Vol. 2. Edited by A. G. Chuchalin. Moscow: Agar. Pp. 118–125.
20. Busse W. W., Godard P., Howarth P. et al. Role and contribution of viral respiratory infections to asthma. Eur. J. Allergy Clin. Immunol. 1993; 48 (17): 57–61.
21. Weiss E. B., Stein M. Bronchial Asthma. 3rd Ed. N.-Y.: Little, Brown and Co. 1993. 1259 p.
22. Johnston S. L., Pattemore P. K., Sanderson G. et al. Community study of role of viral infections in exacerbations of asthma in 9–11 year old children. BMJ. 1995; 10: 1225–1229.
23. Geppe N. A., Revyakina V. A. New international recommendation on bronchial asthma in children PRACTALL. Pulmonology and allergology. Moscow: Atmosfera. 2008; 1: pp. 60–68.
24. Global Strategy of treatment and prophylaxis of bronchial asthma (review 2009). Edited by Chuchalin A. G. Moscow: Atmosfera. 2011. 103 pp.
25. Allergic rhinitis and its impact on asthma (ARIA), 2008 г. Russian allergological journal (appendix). 2010: p. 215.
26. Fever in children. Edited by Saib El-Radkhi A., Kerrol J., Klein N. Moscow: GEOTAR-Media. 2013. Pp. 125–129.
27. El-Radhi A. S., Hogg C. L., Bungre G. K. et al. Effect of oral glucocorticoid treatment on serum inflammatory markers in acute asthma. Arch. Dis. Child. 2000; 83: 158–162.
28. Kulichenko T. V. Montelukast (Singulair) in treatment of chronic diseases in children. Pediatricheskaja farmakologija — Pediatric pharmacology. 2006; 2: pp. 46–54.
29. Knorr B., Franchi L. M., Bisgaard H. et al. Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years. Pediatrics. 2001; 108: 1–10.
30. Bisgaard H., Zielen S., Garcia-Garcia M. L. et al. Montelukast reduces asthma exacerbations in 2-to 5-year-old children with intermittent asthma. Am. J. Respir. Crit. Care Med. 2005; 171: 315–322.
31. L. G. Kuzmenko. To the discussion on human’s constitution, constitutional types and diathesis. Pediatriya. Zhurnal imeni G. N. Speranskogo — Pediatrics. 2005; 5: pp.76–86.
32. Syndrome of enlarged thymus in children. Edited by Martynova M. I., Kuzmenko L. G., Tyrin N. A. Moscow: Publishing house PFRU. 1993. 203 pp.
33. Ivanovskaya T. E., Zayratyanz O. V., Leonova L. V., Voloshchuk I. N. Pathology of thymus in children. St.-Petersburg: SOTIS. 1996. 272 pp.
34. Novikov V. S., Bulavin D. V., Malinin V. V., Simonenkova V. A. Apoptosis of immune system cells. Programmed cell death. Edited by V. S. Novikov. St.-Petersburg: Schience. 1996. Pp. 104–119.
35. King L. B., Vacchio M. S., Ashwell J. D. To be or not to be: mutually antagonistic death signals regulate thymocyte apoptosis. Intern. Arch. Allergy. Immunol. 1994; 105: 355–358.
36. Vaganov P. D., Martynova M. I., Arion V.Ya. et al. Clinicalimmunological characteristics of children with enlarged thymus syndrome and their correction. Russian bulletin of perinatology and Pediatrics. 2001; 46 (3): pp. 59–60.
37. Barcia P., Nelson T. Hyperplasia of the thymus and thymic neoplasm in children. Milit. Med. 1979; 144: 799–801.
38. Matkovskaya T. V. Enlargement of thymus in children. Tomsk: Publishing house of Tomsk University. 1991. 152 pp.
39. Maslov M. S. Diatheses. Multivolume guideline on Pediatrics. Vol. 1. Moscow: Medgiz. 1951. Pp. 505–513.
40. Nesterova I. V., Starchenko A. A., Ivanova S. A., Simbirtsev A. S. Immunotherapy and immunotropic drugs. Handbook of immunotherapy for practice medicine. Edited by Simbirtsev A. S. St.-Petersburg: Dialog. 2002. Pp. 88–99.
41. Kvetnoy I. M., Yarilin A. A., Polyakova V. O., Knyazkin I. V. Neuroimmunoendocrinology of thymus. St.-Petersburg.: DEAN. 2005. 160 pp.
42. Morozov V. G., Khavinson V.Kh., Malinin V. V. Peptide thymomimetics. St.-Petersburg. Science. 2000. 158 pp.
43. Kuzmenko L. G. Treatment and prophylactic service in children with enlarged thymus. Pediatriya. Zhurnal imeni G. N. Speranskogo — Pediatrics. 1996; 4: pp. 63–67.
44. Vaganov P. D., Arion V.Ya., Mikheyeva I. G. Prophylactic and health-improving tactics of children with thymomegalia syndrome management. Pediatriya. Zhurnal imeni G. N. Speranskogo — Pediatrics. 2005; 6: pp. 11–16.
45. Anlehnung an Wann V., von Bermuth H. Diagnostisches Vorgehen beim Verdacht auf einem primaren Immundefekt. J. Lab. Med. 2009; 33 (4): 179–187.
46. Yartsev M. N., Yakovleva K. P., Plakhtiyenko M. V. Immune insuffi ciency and frequently ailing children. Russian allergological journal. Appendix. Collection of thematic articles on a problem “Frequently ailing children”. 2006: pp. 3–31.
47. Allergology and immunology. Edited by Baranov A. A., Khaitov R. M. Moscow: Publishing house of Union of Pediatricians of Russia. 2010. Pp. 169–210.
48. Polyanin D. V., Kartseva O. A., Popova M. A. Clinical and morphological comparison in initial immunodegiciencies in children. Bulletin of PFRU. 2006; 2 (49): pp. 300.
49. Nesterova I. V., Malinovskaya V. V., Tarakanov V. A. et al. Therapy with interferon and immunotherapy in frequently and long-ailing children and adults treatment practice. Capricorn Publishing Inc. 2004. 160 pp.
50. Bossuyt X., Moens L., van Hoeyveld E. et al. Coexistence of (partial) immune defects and risk of reccurent respiratory infections. Clin. Chem. 2007; 53: 124–130.
51. Ribosomal immunocorrection in pediatrician’s practice. Edited by Korovina N. A. Moscow. 2006. 232 pp.
52. Tatochenko V. K., Dorokhova N. F., Shmakova S. G. Ecological phactors and diseases of respiratory organs in children. Ecology and children’s health. Edited by Studenikin M.Ya., Yefimova A. A. Moscow: Medicine. 1998. Pp. 247–272.
53. Tatochenko V. K. Diseases of respiratory organs in children. Moscow: Pediatrician. 2012. Pp. 285–286.
54. Gavalov S. M. Acute pneumonias in children. Selected questions. Novosibirsk: Publishing house of Novosibirsk University. 1990. 276 pp.
55. Vavilova V. P., Perevoshchikova N. I. Educational program for pediatricians and general practitioners “Modern approaches to the management of frequently ailing children”. Kemerovo. 2007. 36 pp.
56. Kovalevskiy V. A. Peculiarities of emotional and volitional development of frequently ailing senior pre-schoolchild. Bulletin of V. P. Astafyev Krasnoyarsk Pedagogical University. 2012; 3: pp. 77–82.
57. Stefani D. V., Veltishchev Yu. E. Clinical immunology of children’s age. Moscow: Medicine. 1996. Pp. 7–
Рецензия
Для цитирования:
Овсянников Д.Ю., Илларионова Т.Ю., Пушко Л.В., Кузьменко Л.Г. ЧАСТО БОЛЕЮЩИЕ ДЕТИ: ЧТО ЕЩЕ КРОМЕ ИНФЕКЦИЙ? Вопросы современной педиатрии. 2013;12(1):74-86. https://doi.org/10.15690/vsp.v12i1.560
For citation:
Ovsyannikov D.Yu., Illarionova T.Yu., Pushko L.V., Kuz'menko L.G. FREQUENTLY ILL CHILDREN: WHAT ELSE BESIDES INFECTIONS? Current Pediatrics. 2013;12(1):74-86. (In Russ.) https://doi.org/10.15690/vsp.v12i1.560
Просмотров:
1096
Послать статью по эл. почте 
