ENRICHMENT OF PRODUCTS FOR CHILDREN FOOD WITH PREBIOTICS: ACHIEVEMENTS AND CHALLENGES
https://doi.org/10.15690/vsp.v12i1.561
Abstract
Since the moment of its formulation, the concept of prebiotics was supported and developed by many researches across the world. The usage of prebiotics for the optimization of the intestinal microflora composition and, therefore, the strengthening of infants health has an increased interest both of scientists and pediatricians. In this article the authors give briefly account on the classification and characteristics of the most common prebiotics, making an emphasis on inulin-type fructans, and show literature and their own data on clinical assessment of different prebiotic products.
About the Authors
A. I. SafronovaRussian Federation
I. Ya. Kon'
Russian Federation
O. V. Georgieva
Russian Federation
References
1. Gibson G. R., Roberfroid M. B. Dietary modulation of the human colonic microbiota — introducing the concept of prebiotic. J. Nutrition. 1995; 125: 1401–1412.
2. Kunz C., Koletzko B. et al. Nutritional and biochemical properties of human milk, part I. General aspects, proteins and carbohydrates. Clin. Perinatol. 1999; 26: 307–333.
3. Kunz C., Baier W. et al. Oligosaccharides in human milk: structural, functional, and metabolic aspects. Ann. Rev. Nutr. 2000; 20: 699–722.
4. Engfer M. B., Stahl B. et al. Human milk oligoccharides are resistant to enzymatic hydrolyses in the upper gastrointestinal tract. Am. J. Clin. Nutr. 2000; 71: 1589–1596.
5. Miller J., McVeagh P. Human milk oligoccharides: 130 reasons to breastfeed. Brit. J. Nutr. 1999; 82: 111.
6. Demigne C., Jacobs H., Moundras C. et al. Comparision of native or reformulated chicory fructans, or non-purified chicory, on rat cecal fermentation and mineral metabolism. Eur. J. Nutr. 2008; 47: 366–374.
7. Roberfroid M., Robertson D. Effect of inulin and oligofructose on health and well-being. Brit. J. Nutr. 2005; 9 (Suppl. 1): 1–27.
8. Roberfroid M. Inulin-type fructans: functional food ingredient. J. Nutr. 2007; 137: 2493–2502.
9. Roberfroid M. Prebiotics: the concept revisited. J. Nutr. 2007; 137 (3, 2): 830–837.
10. Liong M.-T. Roles of probiotics and prebiotics in colon cancer prevention: postulated mechanisms and in vivo evidence. Int. J. Mol. Sci. 2008; 9 (5): 854–863.
11. Griffin I. J., Davila P. M., Abrams S. A. Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes. Brit. J. Nutr. 2002; 87: 187–191.
12. van den Heuvel E. G., Muys T., van Dokkum W. et al. Oligofructose stimulates calcium absorption in adolescents. Am. J. Clin. Nutr. 1999; 69: 544–548.
13. Moro G., Minoli I., Mosca M., Jelinek J., Stahl B., Boehm G. Dosage related bifidogenic effects of galacto- and fructooligosaccharides in formula fed term infants. J. Pediatr. Gastroenterol. Nutr. 2002; 34: 291–295.
14. Savino F., Cresi F., Maccario S., Cavallo F., Dalmasso P., Fanaro S. et al. «Minor» feeding problems during the first month of life: effect of a partially hydrolysed milk formula containing fructo- and galactooligosaccharides. Acta Paediatrica. 2003; 92: 86–90.
15. Boehm G., Fanaro S., Jelinek J., Stahl B., Marini A. Prebiotic concept for infant nutrition. Acta Paediatr. Suppl. 2003; 91 (441): 64–67.
16. Fanaro S., Boehm G., Garssen J., Knol J., Mosca F., Stahl B., Vigi V. Galacto-oligosaccharides and long-chain fructo-oligosaccharides as prebiotics in infant formulas: a review. Acta Paediatr. Suppl. 2005; 94 (449): 22–26.
17. Kim S. H., Lee D. H., Meyer D. Supplementation of baby formula with native inuline has a prebiotic effect in formula-fed babies. Asia Pac. J. Clin. Nutr. 2007; 16: 172–177.
18. Kon I.Ya., Abramova T. V., Pustograyev N. N., Konovalova L. S., Kiseleva Ye. S. A study of new dried adapted milk formula in nutrition of infants. Questions of practical Pediatrics. 2008; 3 (4): pp. 76–81.
19. Kon I.Ya., Abramova T. V., Safronova A. I., Gultikova O. S. Results of multicenter study of clinical efficacy of dried adapted milk formula with dietary fibres in nutrition of infants. Questions of practical Pediatrics. 2010; 5 (2): pp. 29–37.
20. Braegger C., Chmielevska A., Desci T., Kolacek S., Mihatsch W., Moreno L. et al. Supplementation of infant formula with probiotics and/or prebiotics: a systematic review and comment by ESPGHAN Commitee on Nutrition. J. Pediatr. Gastroenterol. Nutr. 2010.
21. Sholtens P., Alles M., van Der Linde E., Knol J. Introduction of solid weaning foods with added prebiotic oligosaccharides affects the composition of the intestinal microflora. J. Pediatr. Gastroenterol. Nutr. 2003; 4 (36): 566.
22. Sholtens P., Alles M., Bindels J. G., van Der Linde E., Tolboom J., Knol J. Bifidogenic effects of solid weaning foods with added prebiotic oligosaccharides: a randomized controlled clinical trial. J. Pediatr. Gastroenterol. Nutr. 2006; 42 (5): 553–559.
23. Saavedra J., Tshernia A. Human studies with probiotics and prebiotics: clinical implications. Brit. J. Nutr. 2002; 87 (Suppl. 2): 241–246.
24. Firmansyah A., Pramila G., Fassler A., Hashke F., Link-Amster H. Improved humoral immune response to measles vaccine in infants receiving infant cereal with fructooligosaccharides. J. Pediatr. Gastroenterol. Nutr. 2000; Abstract 521.
25. Kon I.Ya., Abramova T. V., Georgiyeva O. V. Prebiotics in children’s food products: the study of cereal enriched by prebiotics in nutrition of infants. Questions of children’s dietology. 2008; 6 (1): pp. 66–70.
26. Kon I.Ya., Safronova A. I., Abramova T. V., Pustograyev N. N., Kurkova V. I. Cereals with inulin in nutrition of infants. Russian bulletin of perinatology and Pediatrics. 2012; 3: pp. 106–110.
Review
For citations:
Safronova A.I., Kon' I.Ya., Georgieva O.V. ENRICHMENT OF PRODUCTS FOR CHILDREN FOOD WITH PREBIOTICS: ACHIEVEMENTS AND CHALLENGES. Current Pediatrics. 2013;12(1):87-92. (In Russ.) https://doi.org/10.15690/vsp.v12i1.561