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РИТУКСИМАБ В ПЕДИАТРИЧЕСКОЙ РЕВМАТОЛОГИИ

Аннотация

В статье представлен обзор литературы, посвященный роли В лимфоцитов в патогенезе ревматических заболеваний и применению химерных анти-CD20 моноклональных антител (ритуксимаба) для лечения системной красной волчанки, системных васкулитов, ювенильного дерматомиозита, ювенильного артрита у детей. Результаты исследований свидетельствуют о хорошей переносимости, эффективности и безопасности ритуксимаба в детской ревматологической практике.

Ключевые слова: дети, В лимфоциты, ритуксимаб, лечение, деплеция.
(Вопросы современной педиатрии. – 2010;9(3):54-62)

Об авторах

Е.И. Алексеева
Научный центр здоровья детей РАМН, Москва
Россия


Р.В. Денисова
Научный центр здоровья детей РАМН, Москва
Россия


С.И. Валиева
Научный центр здоровья детей РАМН, Москва
Россия


Т.М. Бзарова
Научный центр здоровья детей РАМН, Москва
Россия


А.О. Лисицин
Научный центр здоровья детей РАМН, Москва
Россия


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Для цитирования:


Алексеева Е., Денисова Р., Валиева С., Бзарова Т., Лисицин А. РИТУКСИМАБ В ПЕДИАТРИЧЕСКОЙ РЕВМАТОЛОГИИ. Вопросы современной педиатрии. 2010;9(3):54-62.

For citation:


Alexeeva E., Denisova R., Valieva S., Bzarova T., Lisitsyn A. RITUXIMAB IN PEDIATRIC RHEUMATOLOGY. Current Pediatrics. 2010;9(3):54-62.

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