Vol 8, No 1 (2009)
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SOCIAL PEDIATRICS AND HEALTH CARE
5-9 823
Abstract
Social orphanhood is and actual problem of the present, affecting all spheres of social life. There are over 1 million of children, practically devoid of parental care in Russia, and it we take account a phenomenon of latent orphanhood, the problem seems to be much more dimensioned. The system of social health has resources for the influence on the question of saving of family education or finding of family by children with chronic diseases, disorders in development, invalids, and children from boarding schools of different departments, including children's homes. Main task of departments of health service are prophylaxis of early disavowals from children, timely revelation of risk factors of social orphanhood in families, modernization of activity of children's houses in the field of creation of conditions of family education, and more wide use of all types of family formations.
Key words: children, orphanhood, invalids.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):5-9)
Key words: children, orphanhood, invalids.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):5-9)
10-12 590
Abstract
The aim of this trial was to evaluate the peculiarities of quality of life (QL) of blind and purblind children, educated in specialized schools. 64 schoolchildren from specialized correction school and 78 schoolchildren from boarding school of Tatarstan Republic in age 8-12 and 13-18 years old took part in this trial. Instrument of this trial was Russian version of general questionnaire Pediatric Quality of Life Inventory – PedsQL4.0. Results of study showed, that quality of life of blind and purblind children was lower then in their healthy coevals, according to opinion of children, their parents and teachers. On the other hand, quality of life of children with vision disorders, educated in different types of correction schools, did not differ.
Key words: quality of life, blind and purblind children.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):10-12)
Key words: quality of life, blind and purblind children.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):10-12)
14-18 1199
Abstract
One of priority tasks in development of method of estimation of a quality of life in children is elaboration of questionnaires. The results of adaptation and validation of QUALIN questionnaire for the estimation of a quality of life in children from 3 months to 3 years old for the purpose of development of Russian version are presented in this article. Obtained data allowed drawing a conclusion that elaborated version of a questionnaire can be used in scientific and clinical trials for the estimation of a quality of life in younger children.
Key words: quality of life, QUALIN questionnaire, younger age.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):14-18)
Key words: quality of life, QUALIN questionnaire, younger age.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):14-18)
ORIGINAL ARTICLES
20-24 565
Abstract
This trial studied the rate of contamination of mucous tunica of throat, nasopharyngeal and palatine tonsils with human papilloma viruses, type 6, 11, 16, 18, 31 and 33. 29 children with recurrent respiratory papillomatosis (RRP) and 57 children hospitalized for planned adenotomy, tonsillotomy or tonsillectomy took part in this trial. Virus in bioptate from removed papillomas was discovered in 100% of patients with RRP (type 6 and (or) 11 in all cases). Despite absence of clinical symptoms of throat papillomatosis, contamination of mucous tunic of throat was discovered in 48% of patients in this group. Children without clinical signs of RRP had virus contamination of upper airways in 44% cases. The rate of contamination of schoolchildren and younger children was comparable.
Key words: children, human papilloma virus, recurrent respiratory papillomatosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):20-24)
Key words: children, human papilloma virus, recurrent respiratory papillomatosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):20-24)
PSYCHO-PHYSIOLOGICAL CHARACTERISTICS OF ADOLESCENTS WITH HIGH RISK OF DEVELOPMENT OF BEER DEPENDENCE
25-29 561
Abstract
The aim of present trial is study of psycho physiological peculiarities of adolescents with high risk of development of beer dependence. 143 schoolchildren from 5-11 form of Archangelsk schools of general education took part in trial. 3 groups of adolescents were formed, depending of summarized indices of beer alcoholization: group of high grade of alcoholization (35.5%), medium grade (45.2%) and low grade (19.3%). Adolescents with high risk of development of beer dependence are characterized with lowering of simple visual-motor and audio-motor response rate, complex visual-motor response rate, complex sensomotor response rate on moving object, decrease of stability of sensomotor processes and attention stability, stability of mental work and mental efficiency depending on time, efficiency in deficit of time and information. These disorders may be used in early diagnostics of beer dependence in structure of primary and secondary psycho prophylactic measures.
Key words: adolescents, beer dependence, psycho physiological peculiarities, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):25-29)
Key words: adolescents, beer dependence, psycho physiological peculiarities, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):25-29)
R.V. Denisova,
E.I. Alexeeva,
V.Yu. Al'bitsky,
I.V. Vinyarskaya,
S.I. Valieva,
T.M. Bzarova,
A.O. Lisitsin,
E.Yu. Gudkova
30-40 1043
Abstract
The article presents a results of evaluation of psychometric properties of Russian versions of PedsQL Rheumatology Module (PedsQL RM) and PedsQL Generic Core Scale (PedsQL GCS) questionnaires in estimation of quality of life in children of 5-18 years old with juvenile arthritis.138 children took part in this trial: 57 patients in age 5-7 years old (middle age 5.86±0.88 years old), 43 – from 8 to 12 years old (middle age 9.69±0.88 years old), and 38 children – from 13 to 18 years old (middle age 13.8±1.03 years old). Estimation of reliability of questionnaires was held with calculation of Cronbach's alpha, constructive validity – with method of “known groups” with the help of analysis of dependence of quality of life indices from index of functional insufficiency (estimated by CHAQ questionnaire). Evaluation of sensitivity was carried out with comparison of quality of life in children (n=24, n=16, n=14) at the initial stage and on 6-th week of treatment with infliximab. Cronbach’s alpha was 0.70-0.91, which testifies to high reliability of Russian versions of PedsQL RM and PedsQL GCS questionnaires. Significant inverse negative relationship of functional insufficiency index reflects validity of Russian versions of PedsQL RM and PedsQL GCS questionnaires. Improvement of quality of life in children with rheumatoid arthritis confirms high sensitivity of Russian versions of PedsQL RM and PedsQL GCS questionnaires. Thus, Russian versions of PedsQL RM and PedsQL GCS questionnaires allow impartial estimation of quality of life in children with juvenile arthritis.
Key words: juvenile arthritis, children, quality of life, PedsQL Rheumatology Module and PedsQL Generic Core Scale, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):30-40)
Key words: juvenile arthritis, children, quality of life, PedsQL Rheumatology Module and PedsQL Generic Core Scale, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):30-40)
41-45 556
Abstract
This article presents results of nephrological and urological diagnostics and treatment of 48 children with dismethabolic nephropathy in age 2-15 years old. Oxalaturia was diagnosed in 75% of patients, uraturia – in 25%, isolated crystaluria – in 47,5%, combination with microeritrocyturia and (or) proteinuria – 52,5%. Besides, increasing of malonic dialdehyde concentration in blood and urine, protein, beta2-microglobulin and nitrites in blood and urine was marked. This fact testifies to instability of cell membranes and presence of disorders of kidney tissue function. Use of Caneohron N in rehabilitation of children with dismethabolic nephropathies in mono- or combined treatment course leads to normalization of level of malonic dialdehyde, nitric oxide, proteinuria and beta2-microglobulin.
Key words: children, dismetabolic nephropathy, treatment, rehabilitation.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):41-45)
Key words: children, dismetabolic nephropathy, treatment, rehabilitation.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):41-45)
LITERATURE REVIEW
46-51 635
Abstract
This review describes basic aspects of neurological pathology in children with juvenile rheumatoid arthritis. Results of reviewed trials show that neurological and cognitive disorders, presenting in patients with juvenile rheumatoid arthritis, worsen patient’s quality of life and need to be corrected with medicaments.
Key words: children, juvenile rheumatoid arthritis, neurological patology.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):46-51)
Key words: children, juvenile rheumatoid arthritis, neurological patology.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):46-51)
LECTURES
52-58 1200
Abstract
This lecture (the first one of planned) describes the structure and function of inborn immunity factors, as a component of system of immunobiological surveillance of organism; also this work gives information of mechanisms of detection of foreign antigens with special classes of phagocytic receptors (appearance-recognizing, toll-like, NOD, mannose, lektine, scavenger, receptors of complement system factors, etc.). Authors describe syndromes of insufficiency of immunobiological surveillance system, developing as a consequence of disorders of reception of foreign agents with phagocytes.
Key words: inborn immunity, adaptive immunity, appearance-recognizing receptors, pathogen-associated molecules, immunopathological syndromes.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):52-58)
Key words: inborn immunity, adaptive immunity, appearance-recognizing receptors, pathogen-associated molecules, immunopathological syndromes.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):52-58)
60-67 589
Abstract
This lecture shows basic conception of problem of vitamin deficiency in schoolchildren at the time of increased educational load (intellectual and physical). It’s marked, that children taking vitamin complexes have optimal concentration of vitamins in blood plasma. All vitamins in vitamin complexes are similar to “natural” ones, presenting in natural food with its chemical structure and biological activity. Opinion that pharmaceutically made vitamins are less assimilated then “natural” is mistaken. Administration of vitamins in complex is more effective then separate use of each of them. As a result, prophylactic use of vitamins strengthens protective forces of child’s organism, favors to normal functioning of nervous system of schoolchildren, increases the resistance to physical loads and recommended to children with nutrition disorders.
Key words: children, vitamins B, education, vitamin complexes.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):60-67)
Key words: children, vitamins B, education, vitamin complexes.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):60-67)
EXCHANGE OF EXPERIENCE
68-71 568
Abstract
This article describes the results of estimation of effectiveness of lactulose (Dupfalac) in preoperative preparation of children with decompensated type of chronic colon stasis. Proved, that administration of this medication normalizes such indices of homeostasis as acid-base balance of blood and microbiocenose of colon by 7days. Use of lactulose decreases patient complaints on nausea, vomiting, abdominal pain, weakness in 1.6 times rarely then in group of children using other laxative medications in preoperative preparation.
Key words: megacolon syndrome, lactulose, dysbacteriosis, blood acid-base balance.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):68-71)
Key words: megacolon syndrome, lactulose, dysbacteriosis, blood acid-base balance.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):68-71)
72-80 636
Abstract
Article presents results of proper investigations of effectiveness of formulas with different protein level: “Baby Samp 1” (13 g/l) and “Baby 1” (15 g/l). The trial included 55 children from 25 days to 3 months old. This trial was open-labelled, comparative, randomized, and prospective. Proved, that milk formula with concentration of protein 13 g/l provide for adequate grouth and development parameters in children of first months of life. This fact was confirmed with dynamics of children’s body weight and stature and increase of protein, albumin and prealbumin levels in plasma. There were no advantages of nutrition with formula with protein level 15 g/l. Concentration of protein in milk formula influences on level of insulin-like growth factor 1 in children of first months of life.
Key words: children of first year of life, artificial feeding, protein concentration, insulin-like growth factor 1.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):72-80)
Key words: children of first year of life, artificial feeding, protein concentration, insulin-like growth factor 1.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):72-80)
81-84 830
Abstract
This trial included 97 children with acute tonsillopharyngitis (angina), acute pharyngitis, laryngitis, otitis media. Ibubrofen suspension (Nurofen for Children) was administrated in standard dose. Good and excellent analgetic and antipyretic result was registered in 75% of patients after 1 day, and satisfactory – in 25% of children. 44 children with different diseases of throat were treated with flurbiprofen as symptomatic anesthetic medication combined with other ones. Pain in throat and deglutitive problems were lessened after 2-3 hours after 1 administration of medication, and further reduction of symptoms was registered every 3 hours. Pain in throat was stopped in 38 children after 3 days of treatment. Thus, ibuprofen suspension and resorption tablets with flurbiprofen provide significant anesthetic effect in children, and they can be used in practice of children’s ENT specialist.
Key words: children, ENT diseases, nonsteroid anti-inflammatory medications.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):81-84)
Key words: children, ENT diseases, nonsteroid anti-inflammatory medications.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):81-84)
85-89 650
Abstract
Authors discuss the problem of constipation in children and modern approach to treatment and prophylaxis of this disorder in children of different age group. Stimulating effectiveness of laxative agents and spasmolytics are analyzed. Effectiveness of sodium picosulfate (Guttalax) in monotherapy was compared with combined treatment with sodium picosulfate and spasmolytic (Buscopan) in children with chronic constipation.
Key words: children, chronic constipation, sodium picosulfate, hyoscine butylbromide.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):85-89)
Key words: children, chronic constipation, sodium picosulfate, hyoscine butylbromide.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):85-89)
90-97 1081
Abstract
Cough is frequent symptom in pediatric practice. Tussive reflex has age-specific and physiological peculiarities. The reasons of cough in children are very heterogeneous, and differ from that ones in adults. Main causes of cough in children are inflammation in upper and lower airways, bronchial asthma, and in early age - foreign body in bronchial tube, malformations of airways, gastroesophageal reflux. The approaches to treatment of cough must consider etiology and pathogenesis of its onset.
Key words: children, cough, airways inflammation, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):90-97)
Key words: children, cough, airways inflammation, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):90-97)
98-103 1953
Abstract
This work characterizes peculiarities of clinical picture of viral diarrhea in children. Effectiveness of dietotherapy of children with acute enteric infection with use of substitutes of breast milk: “Nutrilon Low Lactose”, “Nutrilon Comfort 2”, “Nutrilon Antireflux” was studied. It was proved, that valid dietic correction results in more rapid recovery and provides maintenance of trophic status.
Key words: children, viral enteric infections, dietoterapy.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):98-103)
Key words: children, viral enteric infections, dietoterapy.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):98-103)
104-107 3424
Abstract
This article describes an experience of treatment of children (n=92) with miction disorders – syndrome of hyperactive urinary bladder (HUB) with oxybutynin (Driptane). Treatment resulted in decrease of median grade of disorder of urination from 12.5 marks initially to 5.2 marks after 4 weeks of treatment. This effect remained during 3 following months. Besides, the frequency of urinations was lessened in 23%, urgent feeling of urination – in 46%, urgent incontinence was stopped completely. Symptoms of enuresis were more resistant to treatment, and they were stopped completely in 6 children. Side effects, concerned with therapy, were registered in 3 (3%) children. Thus, oxybutynin in effective and safe medication for treatment of children with urinary disorders – HUB syndrome.
Key words: children, syndrome of hyperactive urinary bladder, treatment, oxybutynin.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):104-107)
Key words: children, syndrome of hyperactive urinary bladder, treatment, oxybutynin.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):104-107)
108-113 882
Abstract
Growth inhibition in children is heterogeneous state, and it may accompany many endocrine, somatic, genetic and chromosome diseases. Generally recognized medications for treatment of somatotropic insufficiency in present times are biosynthetic analogs of human growth hormone (hGH), obtained with DNA-recombinant technology. This article presents the results of estimation of effectiveness of hGH in treatment of children with short stature (n=77) with isolated deficiency of growth hormone, panhypopituitarism, Turner's syndrome, treated with hGH during 3 years. All patients had significant positive dynamics of clinical status, the velocity of grouth increased from 1.9 cm (initial) per year to 11.0 cm (the end of first year), with following decrease to 5.3 cm per year. SDS index of growth had stable tendency to increase: medium SDS index of growth initially was -3.9 SD, on the end of third year – -2.0 SD. It was shown, that treatment with hGH is effective in any types of short stature.
Key words: children, short stature, treatment, human growth hormone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):108-113)
Key words: children, short stature, treatment, human growth hormone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):108-113)
A DOCTOR’S AID
114-120 772
Abstract
This article presents new calendar of immunoprophylaxis in Russia, functioning since 2008, with author’s comments to its innovations. Mass vaccination against influenza was added to other ones, presenting in calendar earlier. The age limits of vaccination against hepatitis B, rubella, and measles were enlarged, and scheme of vaccination against hepatitis B was changed. This article describes new opportunities of immunoprophylaxis, that didn’t find its place in calendar yet.
Key words: children, immunoprophylaxis, vaccination calendar.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):114-120)
Key words: children, immunoprophylaxis, vaccination calendar.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):114-120)
121-124 921
Abstract
This article reviews the role of some microelements in functioning of antioxidant systems of child’s organism. It’s marked, that disorders in children’s nutrition, including deficiency of zinc, selenium and vitamins in ration may lead to some severe diseases of gastrointestinal tract. Balanced dietary intake, including milk foods, fortified by zinc, allows preventing a development of chronic diseases, especially in children in period of social and biological adaptation.
Key words: children, microelements, nutrition.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):121-124)
Key words: children, microelements, nutrition.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):121-124)
125-129 666
Abstract
This article describes a problem of treatment of chronic diseases of ENT-organs, frequently developing on the basis of insufficient reactions of immunity. Also the problems of resistance of widely prevalent bacterial cultures to antibiotics, and administration of medications with not evident effectiveness are marked. Authors present a proper experience of treatment of pharyngeal tonsil with bacterial lysates mixture (IRS 19).
Key words: children, ENT-organs pathology, treatment, bacterial lysates mixture.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):125-129)
Key words: children, ENT-organs pathology, treatment, bacterial lysates mixture.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):125-129)
130-134 587
Abstract
This article presents the review of results of International conference on pneumococcal conjugated vaccines. Main results of international experience in the field of control of pneumococcal infection spreading are analyzed. Authors present modern data of clinical and economic effectiveness and safety of pneumococcal conjugated vaccine RCV-7, and describe experience of administration of vaccines of next generation – PCV-10 and PCV-13.
Key words: children, pneumococcal infections, prophylaxis, vaccines.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):130-134)
Key words: children, pneumococcal infections, prophylaxis, vaccines.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):130-134)
CLINICAL OBSERVATIONS
135-141 524
Abstract
This article presents a case report of juvenile ankylosing spondylitis and severe uveitis. A successful treatment with biological agent adalimumab was described. Administration of this medication induced the remission of uveitis, and it allowed surgical treatment of complicated cataract. Treatment of adalimumab resulted in increase of acuity of vision and improvement of quality of life.
Key words: children, juvenile ankylozing spondylitis, rheumatoid uveitis, adalimumab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):135-141)
Key words: children, juvenile ankylozing spondylitis, rheumatoid uveitis, adalimumab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):135-141)
142-146 654
Abstract
Authors give a description of spontaneous dissection (SD) of extra- and intracranial arteries in 5 children (4 boys and 1 girl) in age 5-15 years old. SD in 4 children was developed as ischemic stroke, and in 1 patient – as transitory ischemic attack. SD was provoked by alcoholic beverage, movement of head, straining effort at defecation. Magnetic resonance angiography in acute period and in 1.5 months and later allowed restoration of partial and complete arterial permeability. Magnetic resonance imaging in all patients showed infarction in basin of affected arteries. Clinical and laboratory signs of thrombophilia were absent. Authors made a conclusion, that diagnosis of SD is based on complex evaluation of clinical sign and repeated angiography data. Differentiation is carried out between SD and thrombosis of intracranial arteries.
Key words: children, spontaneous intracranial dissection, ischemic stroke.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):142-146)
Key words: children, spontaneous intracranial dissection, ischemic stroke.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):142-146)
SHORT REPORTS
HISTORY OF PEDIATRICS
ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)
ISSN 1682-5535 (Online)
