Vol 8, No 3 (2009)
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SOCIAL PEDIATRICS AND HEALTH CARE
5-9 528
Abstract
Authors of the article put questions of qualitative higher education of pediatricians, necessity of addition of practical work hours in pediatric and maternity care institutions. Also the article describes the ways of skills acquisition corresponding to the tasks of priority national project «Health» with future specialists.
Key words: children, education, pediatricians, national project «Health».
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):5-9)
Key words: children, education, pediatricians, national project «Health».
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):5-9)
10-13 1320
Abstract
This article describes an information system for physicians working in general education institutes, which is named «Detection, correction and prophylaxis of musculoskeletal system disorders in students of general education institutes». This system was created for the purpose of improving diagnostics of initial stages of musculoskeletal system in schoolchildren, detecting of risk factors, and for the provision of timely prophylaxis during school education. The system was based on classification of functional disorders and initial stages of diseases of musculoskeletal system in schoolchildren, developed by authors of present article, and methods of medical examination and organization of this work.
Key words: schoolchildren, musculoskeletal system, diagnostics, classification, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):10-13)
Key words: schoolchildren, musculoskeletal system, diagnostics, classification, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):10-13)
14-17 574
Abstract
This article presents data of prevalence of HIV-infection in Russian Federation and St.-Petersburg. Main attention was given to problem of HIV-infection in fertile women, ways of viral transmission. Authors note that role of viral transmission by sexual contact in last years became more actual. The state of health in children, born from HIV-positive women was characterized by basic indices: physical and psychical development, morbidity, quality of life. Authors pay attention on problem of social orphan hood in children with perinatal contact with HIV-infection.
Key words: HIV, children, prevalence, indices of health.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):14-17)
Key words: HIV, children, prevalence, indices of health.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):14-17)
ORIGINAL ARTICLES
18-26 495
Abstract
The article presents results of study of inhibitor TNF α — infliximab — on quality of life in patients with juvenile arthritis, refractory to standard immunosuppressive treatment. In 1.5 months after the beginning of treatment, the quality of life increased in 98% of patients; and in one year, the rates of physical functioning were similar to it in healthy children the same age.
Key words: children, juvenile arthritis, quality of life, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):18-26)
Key words: children, juvenile arthritis, quality of life, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):18-26)
27-34 422
Abstract
Headache is the more often seen complaint in patient with rheumatoid arthritis (RA) at the visit to the neurologist. The objective of this study is analysis of headaches in children with different types of RA. 166 patients with different types of rheumatoid arthritis were examined, 65 (39,1%) children had complaints to the headaches. All patients with complaints to the headaches underwent complex examination — taking neurological history, neurological examination, and radiography of cervical part of spinal column in 2 projections, Doppler sonography of cervical vessels, eye grounds examination. Analysis of symptoms of headaches makes possible dividing it to the main types in patients with rheumatoid arthritis: craniocervicalgia, vascular headaches, and secondary headaches on the ground of RA exacerbation, intoxication, and steroid arterial hypertension, and stress headaches. It was shown, that headaches can be a result of both disease and its antirheumatic treatment.
Key words: children, headaches, juvenile arthritis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):27-34)
Key words: children, headaches, juvenile arthritis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):27-34)
LITERATURE REVIEW
35-41 566
Abstract
This article analyzes questions of quadrivalent vaccine Gardasil use for the protection of human papilloma virus (HPV) type 6, 11, 16, and 18, responsible to 70% of carcinoma of uterine cervix cases, and 90% of anogenital condylomas. The results of wide ranging trials show that vaccine is effective in almost 100% of cases for the prevention of pre oncological intraepithelial dysplasia of uterine cervix, vulva, and vagina, anogenital condylomas, caused by vaccine types of HPV. Studies describe vaccine's high immunogenicity and safety. The vaccine was included in immunizations schedule in many countries. Obtained data give us hope that vaccination against uterine cervix cancer will be included in Russian National immunizations schedule in the immediate future.
Key words: human papilloma virus, carcinoma of uterine cervix, quadrivalent vaccine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):35-41)
Key words: human papilloma virus, carcinoma of uterine cervix, quadrivalent vaccine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):35-41)
42-47 939
Abstract
This article presents the literature data on physiological role of vitamins group B, prevalence of vitamins of this group deficiency in children, needs of children in vitamins group B, and possible methods of prophylaxis and correction of vitamins deficient states.
Key words: children, vitamins group B, deficiency, health.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):42-47)
Key words: children, vitamins group B, deficiency, health.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):42-47)
48-53 639
Abstract
This article presents the data on iodine physiological role, the prevalence and the reasons of iodine deficiency among children in Russian Federation. Authors describe negative influence of iodine deficiency on somatic health, cognitive functions and fine motor coordination forming in children of different age, indices of linear growth and harmonicity of physical development. The data on Russian and foreign trials studying modern methods of prophylaxis of iodine deficiency, was presented.
Key words: children, iodine, deficiency, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):48-53)
Key words: children, iodine, deficiency, prophylaxis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):48-53)
LECTURES
54-65 534
Abstract
The lecture analyzes a modern data on etiology, pathogenesis, and principles of treatment of primary and secondary insufficiency of innateimmune mechanisms, which are the result of disorders in two systems: phagocyte cells and complement.
Key words: immunobiological response system surveillance, incomplete phagocytosis, phagocytal insufficiency, complement system insufficiency.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):54-65)
Key words: immunobiological response system surveillance, incomplete phagocytosis, phagocytal insufficiency, complement system insufficiency.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):54-65)
66-75 870
Abstract
Hemophagocytal lymphohistiocytosis is a rare and frequently fatal disorder of immune response regulation, based on defects of cell cytotoxicity and hyper production of pro inflammatory cytokines. This disease is devided to genetically determinate types of hemophagocytal lymphohistiocytosis and secondary hemophagocytal syndromes, associated to infections, malignant neoplasm, autoimmune disease and immunodeficiency. The article gives a brief description of pathogenesis, clinical symptoms, and methods of hemophagocytal lymphohistiocytosis treatment.
Key words: hemophagocytal lymphohistiocytosis, immunosuppression, ciclosporin A, etoposide, dexamethasone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):66-75)
Key words: hemophagocytal lymphohistiocytosis, immunosuppression, ciclosporin A, etoposide, dexamethasone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):66-75)
76-81 818
Abstract
Pericarditis maybe caused by different agents: viruses, bacteria, tuberculosis, and it may be autoimmune. All these types of diseases have similar clinical signs, but differ by prevalence, prognosis and medical tactics. Due to achievements of radial methods of visualization, molecular biology, and immunology, we have an opportunity to provide early specific diagnostics and etiological treatment of inflammatory diseases of pericardium. The second part of lecture presents main principles of differential diagnostics of specific types of pericarditis, gives characteristics of several often accruing types of disease, and describes treatment and tactics of management of patients with pericarditis.
Key words: children, pericarditis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):76-81)
Key words: children, pericarditis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):76-81)
82-87 475
Abstract
This article present a general review on pneumococcal infection, its prevalence, clinic types in children in Russia and worldwide. Description of S. pneumoniae serotypes' distribution and its influence at clinical manifestation of pneumococcal infection and vaccination effectiveness is provided. Author evaluates perspectives of pneumococcal infection prevention by vaccination with pneumococcal conjugated 7-valent vaccine in Russia.
Key words: children, pneumococcal infection, vaccination, pneumococcal conjugated 7 valent vaccine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):82-87)
Key words: children, pneumococcal infection, vaccination, pneumococcal conjugated 7 valent vaccine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):82-87)
EXCHANGE OF EXPERIENCE
E.I. Alexeeva,
A.O. Lisitsin,
N.A. Karagulyan,
O.L. Lomakina,
S.I. Valieva,
T.M. Bzarova,
R.V. Denisova,
E.Yu. Gudkova,
A.M. Chomakhidze,
K.B. Isaeva
88-94 607
Abstract
This article presents the results of a trial, studying effectiveness and safety of adalimumab in treatment of 16 patients with different types of juvenile arthritis, refractory to standard immunosuppressive treatment and infliximab. The treatment with adalimumab provided the development of articular syndrome and uveitis remission, decreasing and normalization of laboratory indices of disease activity, lessening of disabling disorders rate, increase of quality of life in all patients. The tolerance to adalimumab was satisfactory: there was no any adverse event related to treatment.
Key words: children, juvenile arthritis, treatment, uveitis, adalimumab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):88-94)
Key words: children, juvenile arthritis, treatment, uveitis, adalimumab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):88-94)
95-98 890
Abstract
Palatine tonsil hypertrophy is one of the most frequent cases of nasal obstruction in children. Perfection of conservative treatment of palatine tonsil hypertrophy is important direction in prophylaxis of inflammatory diseases of nasal cavity and paranasal sinuses. This article presents an experience of treatment with mometasone furoate (Nasonex) in children (n = 20) in age 6–15 years old with medium and severe nasal obstruction, caused by palatine tonsil hypertrophy. It was shown that treatment during 4 weeks, including mometasone furoate, resulted in increase of summary volumetric air flow rate, passing through the nasal cavity (from 304 ± 24 to 404 ± 22 sm3/s, p = 0.002), and decrease of summary resistance in fixed pressure point (from 0.64 ± 0.08 to 0.40 ± 0.02 Pa/sm3/s, p = 0.003). The degree of choanal obstruction was decreased at the time of study from 72% to 47%. Thus, treatment with mometasone furoate favors to reduction of volumetric size of palatine tonsil and reduction of endoscopic controlled choanal obstruction.
Key words: children, palatine tonsil hypertrophy, treatment, mometasone furoate.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):95-98)
Key words: children, palatine tonsil hypertrophy, treatment, mometasone furoate.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):95-98)
T.E. Borovik,
V.A. Skvortsova,
S.G. Makarova,
O.K. Netrebenko,
O.L. Lukoyanova,
Yu.S. Akoev,
N.N. Semenova,
T.N. Stepanova
99-103 531
Abstract
Authors analyzed a data on composition of modern industrially produced paps. The terms «pro and prebiotical products» was defined. It was shown, that these products influenced on composition of intestinal micro flora, functional state of gastrointestinal tract, and opportunity of prophylaxis of alimentary allergy in children in first year of life. This article describes good tolerance and significant effectiveness of milk free pap «Pomogayka» containing oats, wheat and prunes, enriched with sinbiotics: oligofructose, inulin, and bifidobacterium.
Key words: children in infancy, probiotics, prebiotics, alimentary allergy, intestinal disbiosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):99-103)
Key words: children in infancy, probiotics, prebiotics, alimentary allergy, intestinal disbiosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):99-103)
104-107 641
Abstract
This article presents results of clinical observation, carried out for the purpose of evaluation of effectiveness of immunotherapy for preventing of relapse of acute respiratory infection in group of frequently ailing children. This trial included 300 patients in age from 3 to 15 years old, which had 6 of more episodes of acute respiratory infection during last years. Synthetic dipeptide pidotimoid was prescribed to all patients with insufficient function of immune system. Patients from pidotimoid group had significantly lower pate of relapse of respiratory infections and more rapid recovery.
Key words: frequently ailing children, acute respiratory infection, treatment, prophylaxis, pidotimoid.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):104-107)
Key words: frequently ailing children, acute respiratory infection, treatment, prophylaxis, pidotimoid.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):104-107)
108-113 528
Abstract
Authors analyzed the results of dynamical observation and outcomes of pregnancy in 18 706 women. The ultrasonic scanning (US) was performed on 11–14 weeks of pregnancy in US_diagnostics department of maternity hospital № 5, Krasnoyarsk. Different congenital malformations (CM) and hereditary diseases (HD) was detected in 423 fetuses. 82.5% of CM and HD cases was diagnosed with the help of US in prenatal period. Presence of CM in fetus was accompanied with increase of chromosome pathology more then 10 times higher (on 14.7%). On the whole, unfavorable perinatal outcomes were detected in 293 (69.3%) cases of CM and HD in fetuses or newborn.
Key words: fetus, congenital malformations, hereditary diseases, prenatal diagnostics.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):108-113)
Key words: fetus, congenital malformations, hereditary diseases, prenatal diagnostics.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):108-113)
A DOCTOR’S AID
114-119 611
Abstract
Varicella is a disease which can be stopped by methods of specific prophylaxis. At the same time, there are no official recommendations on vaccinal prophylaxis of varicella in Russia nowadays. The article presents the answers to the most frequently asked questions of pediatrists concerning vaccination techniques, its effectiveness and safety, and vaccination in epidemic nidus. Special attention was given to the questions of vaccinal prophylaxis of varicella in immunocompromised patients.
Key words: varicella, prophylaxis, vaccination.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):114-119)
Key words: varicella, prophylaxis, vaccination.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):114-119)
120-122 885
Abstract
This article describes a role of calcium, phosphorus, vitamins D, A and group of vitamins B in growth and development of adolescents. Balances composition of complex medication «Kalcinova» allow preventing of deficient state in children in prepubertal period.
Key words: adolescents, calcium, vitamins, nutrition.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):120-122)
Key words: adolescents, calcium, vitamins, nutrition.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):120-122)
123-126 441
Abstract
The increase of prevalence of allergic diseases makes specialists for developing of new methods of primary prophylaxis. This article presents modern approach to opportunities of primary prophylaxis of allergic diseases with diet in children.
Key words: alimentary allergy, children, prophylaxis, allergic diseases.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):123-126)
Key words: alimentary allergy, children, prophylaxis, allergic diseases.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):123-126)
127-131 507
Abstract
Present article gives a description of main clinical signs, diagnostic criteria and principles of treatment of somatotropic insufficiency in children. Author presents an experience of screening analysis of microsomia in children in Archangelsk region. It was shown, that introduction of program of education with principles of diagnostics of endocrine growth inhibition in children to the doctors of primary care service, may significantly increase the exposure of somatotropic insufficiency in children's population.
Key words: children, somatotropic insufficiency, diagnostics.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):127-131)
Key words: children, somatotropic insufficiency, diagnostics.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):127-131)
CLINICAL OBSERVATIONS
K.B. Isaeva,
E.I. Alexeeva,
R.V. Denisova,
T.M. Bzarova,
S.I. Valieva,
A.O. Lisitsin,
E.Yu. Gudkova,
E.L. Semikina,
E.A. Kopyl'tsova
132-138 517
Abstract
The article gives a case report on patient with severe systemic type of juvenile arthritis, refractory to treatment with classical immuno suppressants and blocker of tumor necrotizing factor Successive application of biological agent — rituximab was described. In 9 weeks, extra articular symptoms of disease and acute inflammatory lesions in joints were stopped, and functional activity of child increased. Presented case report demonstrates high effectiveness of rituximab: patient with severe systemic type of juvenile arthritis has clinical and laboratory remission of disease during 12 months.
Key words: children, juvenile rheumatoid arthritis, rituximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):132-138)
Key words: children, juvenile rheumatoid arthritis, rituximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):132-138)
SHORT REPORTS
INFORMATION FROM THE UNION OF PEDIATRICIANS OF RUSSIA
HISTORY OF PEDIATRICS
ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)
ISSN 1682-5535 (Online)
