Увеиты, ассоциированные с ювенильным идиопатическим артритом. Современное состояние проблемы: вопросы эпидемиологии, патогенеза и клиники
https://doi.org/10.15690/vsp.v23i6.2832
Аннотация
Увеит является наиболее частым внесуставным проявлением ювенильного идиопатического артрита (ЮИА) и при отсутствии адекватного лечения приводит к развитию серьезных осложнений со стороны органа зрения, таких как катаракта, вторичная глаукома, отслойка сетчатки, лентовидная дистрофия роговицы. Наличие данной патологии снижает качество жизни пациентов и может приводить к значительными социально-экономическими потерям, как из-за прямых медицинских затрат, так и за счет потери трудоспособности, поскольку способно повлечь за собой полную потерю зрения. Увеиты детского возраста составляют примерно 5–10% от числа всех увеитов в популяции, однако их число увеличивается в последние годы. Этиология и патогенез увеита, ассоциированного с ЮИА, остаются недостаточно изученными, несмотря на довольно известную взаимосвязь увеита с ЮИА. Увеиты у детей сложны в диагностике в рутинной педиатрической практике как из-за особенностей течения (бессимптомное/малосимптомное), так и по причине сложностей в вербальной коммуникации и обследовании (дети раннего возраста), что представляет серьезную клиническую проблему. В статье представлены современные данные, касающиеся эпидемиологии, патогенеза, клинических проявлений, терминологии ЮИА-ассоциированных увеитов.
Ключевые слова
При поддержке: Отсутствует.
Об авторах
А. А. Яковлев
ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России
Россия
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Россия
Санкт-Петербург
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Т. Н. Никитина
ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России
Россия
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Санкт-Петербург
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М. М. Костик
ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России
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Михаил Михайлович Костик - доктор медицинских наук, профессор кафедры госпитальной педиатрии
194100, Санкт-Петербург, ул. Литовская, д. 2
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Рецензия
Для цитирования:
Яковлев А.А., Никитина Т.Н., Костик М.М. Увеиты, ассоциированные с ювенильным идиопатическим артритом. Современное состояние проблемы: вопросы эпидемиологии, патогенеза и клиники. Вопросы современной педиатрии. 2024;23(6):424-437. https://doi.org/10.15690/vsp.v23i6.2832
For citation:
Yakovlev A.A., Nikitina T.N., Kostik M.M. Juvenile Idiopathic Arthritis Associated Uveitis. Current Status: Epidemiology, Pathogenesis, and Clinical Issues. Current Pediatrics. 2024;23(6):424-437. (In Russ.) https://doi.org/10.15690/vsp.v23i6.2832
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