МЕСТО ИБУПРОФЕНА В ТЕРАПИИ БОЛИ У ДЕТЕЙ
https://doi.org/10.15690/vsp.v11i1.131
Аннотация
В статье представлены результаты терапевтической эффективности ибупрофена при лечении болевого синдрома у детей. Обоснованность применения препарата для купирования боли у детей не вызывает сомнений. Его анальгетический эффект подтвержден в клинических исследованиях у больных с мигренью и ЛОР-болезнями. В статье также обобщаются данные международного опыта применения ибупрофена при ювенильных артритах.
Об авторе
Р. В. Денисова
Научный центр здоровья детей РАМН, Москва
Россия
Россия
Денисова Рина Валериановна, кандидат медицинских наук, научный сотрудник ревматологического отделения НЦЗД РАМН
Адрес: 119991, Москва, Ломоносовский проспект, д. 2, тел.: (499) 134-14-94, e-mail: denisonarv@yandex.ru
Список литературы
1. Van Dijk A., McGrath P. A., Pickett W. et al. Pain prevalence in nine- to 13-year-old schoolchildren // Pain Res Manag. — 2006; 11: 234–240.
2. Perquin C. W., Hazebroek-Kampschreur A. A., Hunfeld J. A. et al. Pain in children and adolescents: a common experience // Pain. — 2000; 87: 51–58.
3. Merlijn V. P., Hunfeld J. A., van der Wouden J. C. et al. Psychosocial factors associated with chronic pain in adolescents // Pain. — 2003; 101: 33–43.
4. Slade G. D. Epidemiology of dental pain and dental caries among children and adolescents // Community Dent Health. — 2001; 18 (4): 219–227.
5. McGrath P. Chronic pain in children. In: Crombie I., Linton S., LeResche L., Von Korff M., editors. Epidemiology of Pain. — Seattle: IASP Press, 1999. — P. 81–102.
6. Goes P. S., Watt R. G., Hardy R., Sheiham A. Impacts of dental pain on daily activities of adolescents aged 14–15 years and their families // Acta Odontol Scand. — 2008; 66 (1): 7–12.
7. Walker S. M. Pain in children: recent advances and ongoing challenges // BJA. — 2008; 101 (1): 101–110.
8. Lee B. O., Chaboyer W., Wallis M. Predictors of health-related quality of life 3 months after traumatic injury // J. Nurs. Scholarsh. — 2008; 40 (1): 83–90.
9. Vetter T. R. A clinical profile of a cohort of patients referred to an anesthesiology-based pediatric chronic pain medicine program // Anesth Analg. — 2008; 106 (3): 786–794.
10. Lesko S. M., Mitchell A. A. An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial // JAMA. — 1995; 273 (12): 929–933.
11. Southey E. R., Soares-Weiser K., Kleijnen J. Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever // Curr. Med. Res. Opin. — 2009; 25 (9): 2207–2222.
12. Perrott D. A., Piira T., Goodenough B., Champion G. D. Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis // Arch. Pediatr. Adolesc. Med. — 2004; 158 (6): 521–526.
13. Pierce C. A., Voss B. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review // Ann. Pharmacother. — 2010; 44 (3): 489–506.
14. Сайгитов Р. Т. Эффективность ибупрофена в терапии боли у детей: систематический обзор результатов рандомизирован- ных контролируемых исследований // Вопросы современной педиатрии. — 2010; 9 (6): 52–62.
15. Moore P. A., Acs G., Hargreaves J. A. Postextraction pain relief in children: a clinical trial of liquid analgesics // Int. J. Clin. Pharmacol Ther Toxicol. — 1985; 23 (11): 573–577.
16. McGaw T., Raborn W., Grace M. Analgesics in pediatric dental surgery: relative efficacy of aluminum ibuprofen suspension and acetaminophen elixir // ASDC J. Dent. Child. — 1987; 54 (2): 106–109.
17. Evers S., Rahmann A., Kraemer C. et al. Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen // Neurology. — 2006; 67 (3): 497–499.
18. Lewis D. W., Kellstein D., Burke B. et al. Children’s ibuprofen suspension for the acute treatment of pediatric migraine headache // Headache. — 2002; 42: 780–786.
19. Hamalainen M. L., Hoppu K., Valkeila E. et al. Ibuprofen or acetaminophen for the acute treatment of migraine in children: a double-blind, randomized, placebo-controlled, crossover study // Neurology. — 1997; 48: 102–107.
20. Bertin L., Pons G., d'Athis P. et al. Randomized, double–blind, multicenler, controlled trial of ibuprofen versus acetaminophen (paracetamol) and placebo for treatment of symptoms of tonsillitis and pharyngitis in children // J. Pediatr. — 1991; 119 (5): 811–814.
21. Schachtel B. P., Thoden W. R. A placebo-controlled model for assaying systemic analgesics in children // Clin. Pharmacol Ther. — 1993; 53 (5): 593–601.
22. Bertin L., Pons G., d'Athis P. et al. A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children // Fundam. Clin. Pharmacol. — 1996; 10 (4): 387–392.
23. Shepherd M., Aickin R. Paracetamol versus ibuprofen: a randomized controlled trial of outpatient analgesia efficacy for paediatric acute limb fractures // Emerg. Med. Australas. — 2009; 21 (6): 484–490.
24. Clark E., Plint A. C., Correll R. et al. A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma // Pediatrics. — 2007; 119 (3): 460–467.
25. Drendel A. L., Gorelick M. H., Weisman S. J. et al. A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain // Ann. Emerg. Med. — 2009; 54 (4): 553–560.
26. Friday J. H., Kanegaye J. T., McCaslin I. et al. Ibuprofen provides analgesia equivalent to acetaminophen-codeine in the treatment of acute pain in children with extremity injuries: a randomized clinical trial // Acad. Emerg. Med. — 2009; 16 (8): 711–716.
27. Koller D. M., Myers A. B., Lorenz D., Godambe S. A. Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children // Pediatr Emerg. Care. — 2007; 23 (9): 627–633.
28. Silver S., Gano D., Gerretsen P. Acute treatment of paediatric migraine: a meta-analysis of efficacy // J. Paediatr. Child. Health. — 2008; 44 (1–2): 3–9.
29. Rabbie R., Derry S., Moore R. A., McQuay H. J. Ibuprofen with or without an antiemetic for acute migraine headaches in adults // Cochrane Database Syst. Rev. — 2010; 10: CD008039.
30. Gunner K. B., Smith H. D., Cromwell P. F., Yetman R. J. Practice guideline for diagnosis and management of migraine headaches in children and adolescents: Part One // J. Pediatr. Health. Care. — 2007; 21 (5): 327–332.
31. Fuhlbrigge R. C., Chaiban R. The immune system, the skin, and childhood rheumatic disease // Curr. Rheumatol. Rep. — 2011; 13 (2): 103–109.
32. Dannecker G. E., Quartier P. Juvenile idiopathic arthritis: classification, clinical presentation and current treatments // Horm. Res. — 2009; 72 (1): 4–12.
33. Martini A., Lovell D. J. Juvenile idiopathic arthritis: state of the art and future perspective // Ann. Rheum. Dis. — 2010; 69 (7): 1260–1263.
34. Rainsford K. D. Anti-inflammatory drugs in the 21st century // Subcell. Biochem. — 2007; 42: 3–27.
35. Jacqz-Aigrain E., Anderson B. J. Pain control: non-steroidal antiinflammatory agents // Semin. Fetal. Neonatal Med. — 2006; 11 (4): 251–259.
36. Steans A., Manners P. J., Robinson I. G. A multicentre, long-term eva luation of the safety and efficacy of ibuprofen syrup in children with juvenile chronic arthritis // Br. J. Clin. Pract. — 1990; 44 (5): 172–175.
37. Giannini E. H., Brewer E. J., Miller M. L. et al. Ibuprofen suspension in the treatment of juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group // J. Pediatr. — 1990; 117 (4): 645–652.
38. Goldenstein-Schainberg C., Yoshinari N. H. Drug treatment in juvenile chronic arthritis // Rev. Hosp. Clin. Fac. Med. Sao Paulo. — 1997; 52 (2): 90–95.
39. Hollingworth P. The use of non-steroidal anti-inflammatory drugs in paediatric rheumatic diseases // Br. J. Rheumatol. — 1993; 32 (1): 73–77.
40. Autret-Leca E. A general overview of the use of ibuprofen in paediatrics // Int. J. Clin. Pract. — 2003; 135: 9–12.
41. Van den Anker J. N. Use of ibuprofen in paediatric populations // J. R. Soc. Med. — 2007; 100: 18–22.
42. Rainsford K. D. Ibuprofen: pharmacology, efficacy and safety // Inflammopharmacology. — 2009; 17 (6): 275–342.
43. Flato B., Vinje O., Forre O. Toxicity of antirheumatic and antiinflam matory drugs in children // Clin. Rheumatol. — 1998; 17 (6): 505–510.
44. Leroy S., Mosca A., Landre-Peigne C. et al. Ibuprofen in childhood: evidence-based review of efficacy and safety // Arch. Pediatr. — 2007; 14 (5): 477–484.
45. Алексеева Е. И., Литвицкий П. Ф. Ювенильный ревматоидный артрит. — М.: ВЕДИ, 2007. — 368 с.
Рецензия
Для цитирования:
Денисова Р.В. МЕСТО ИБУПРОФЕНА В ТЕРАПИИ БОЛИ У ДЕТЕЙ. Вопросы современной педиатрии. 2012;11(1):46-50. https://doi.org/10.15690/vsp.v11i1.131
For citation:
Denisova R.V. IBUPROFEN IN PAIN TREATMENT IN CHILDREN. Current Pediatrics. 2012;11(1):46-50. (In Russ.) https://doi.org/10.15690/vsp.v11i1.131
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