Vol 9, No 5 (2010)
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EDITORIAL
5-9 765
Abstract
Authors analyzed materials on modern estimation of health from a position of its loss on the stage of self-feeling forming from optimal to maximal level of disease (death). Indicators used for correct evaluation of health in foreign and Russian practice are presented. Specialists of Scientific Center of Children’s Health, Russian Academy of Medical Sciences, developed conception of decreasing of preventable health loss as a consequence of chronic diseases, disability and death. This conception is newly developed concerning to children.
Key words: preventable health loss, children, morbidity, disability, mortality.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):5-9)
Key words: preventable health loss, children, morbidity, disability, mortality.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):5-9)
SOCIAL PEDIATRICS AND HEALTH CARE
10-13 526
Abstract
The article illustrates results from a study of the quality of life of adolescents aged 15–17 living in a closed administrative territorial unit (town of Ozersk) using the questionnaire PedsQL 4.0. It describes the questionnaire survey of 309 children and their parents with the comparison group made up of 298 families from a nearby town. On the whole, no differences were identified in the overall assessment of quality of life indicators in both groups, which indicates there is no impact of a specific town on this category of population.
Key words: adolescents, quality of life, closed administrative territorial unit.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):10-13)
Key words: adolescents, quality of life, closed administrative territorial unit.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):10-13)
ORIGINAL ARTICLES
14-16 688
Abstract
Authors examined 62 children with gastroesophageal reflux (GER), 39% of these children were in pre-pubertal period (9–12 years old) and 61% — in pubertal period (13–17 years old). Electrogastrography (EGG) performed in the morning on an empty stomach during 15–20 min showed that children 9–12 years old predominantly have tachigastria (5.8 ± 2.4 cycle/min). In children 13–17 years old bradigastria (1.6 ± 1.0 cycle/min) was more common (in 68% of children). Amplitude of waves in children 9–12 years old was similar to hyperkinetic type of EGG (55.4 ± 15/7 mm). 68% of children 13–17 years old had hypokinetic type of EGG with wave amplitude 18.4 ± 7.5 mm. Thus, the study showed that disorders of motoric function of stomach are different in different age. Children in pre-pubertal period have hyperkinetic activity or gastric muscles, and in pubertal period GER is characterized by low frequency and amplitude of gastric contractions.
Key words: children, adolescents, gastroesophageal reflux disease, motor function of stomach, electrogastrography.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):14-15)
Key words: children, adolescents, gastroesophageal reflux disease, motor function of stomach, electrogastrography.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):14-15)
18-23 574
Abstract
The objective of present research was studying of influence of co-enzyme Q10 (Kudesan) on cardiovascular system in children with myocardial dystrophy (MCD). Patients were divided on two comparable groups (n = 20 and n = 28) according to clinical symptoms of MCD, changes on electrocardiogram (ECG) and results of echocardiography. Patients received non-drug means (massage, physical training in treatment regimen, psycho- and reflexotherapy) and vasoactive, nootropic and sedative medications; patients from 2nd group were additionally treated with co-enzyme Q10 during 4 weeks. It was shown that inclusion of co-enzyme Q10 in complex treatment of MCD resulted in beneficial effect on self-feeling of child, favored to disappearance of repolarization disorders on ECG and increase of ejectional fraction. Thus, using of co-enzyme Q10 in complex treatment of children with MCD is reasonable.
Key words: children, myocardial dystrophy, co-enzyme Q10, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):18-23)
Key words: children, myocardial dystrophy, co-enzyme Q10, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):18-23)
24-28 535
Abstract
Analysis of morbidity with airways (including pneumonia), ear and mastoid bone diseases in children in 2003–2009 years was performed on the basis of City Organizational-Methodical Center of Assessment and Prognosis of Mother’s and Child’s Health, St.-Petersburg. The data was presented in summary documents for children 0–14 years old (form № 12) and for infants (form № 31). Growth of morbidity with airways pathologies and pneumonias during last 7 years, remaining mortality due to pneumonias in hospitals and tendency to its increase in infants, stable quantity of patients with otitis show necessity of inclusion of effective and modern prophylactic measures including vaccination against pneumococcal infections.
Key words: children, morbidity, diseases of airways, diseases of ear and mastoid bone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):24-28)
Key words: children, morbidity, diseases of airways, diseases of ear and mastoid bone.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):24-28)
30-34 640
Abstract
Authors give information on limits of population norm for expiratory and inspiratory resistance by the interrupter technique indices (RINTexp and RINTinsp accordingly) in 214 healthy children 3–6 years old. Estimation of RINT was performed with spirograph Super Spiro with MicroRint module. Parameters of RINTexp and RINTinsp are similar in boys and girls. RINTexp depends on height of a child. Information on limits of normal rates is presented in this article, and this data can be used in diagnostics of respiratory pathology.
Key words: children, age, resistance of airways, RINT, norm.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):30-34)
Key words: children, age, resistance of airways, RINT, norm.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):30-34)
36-41 478
Abstract
An influence of ribosomal-proteoglycan complex (Ribomunyl) on respiratory system in treatment and rehabilitation of 40 children with recurrent stenosing laryngotracheitis developed on the basis of respiratory viral infections was studied. Inclusion of this drug into complex of treatment and rehabilitation resulted in normalization of lungs’ ventilation and threshold sensitivity of airways, decreasing of common IgE and nitric oxide in these patients. The effect means significant decrease of persistent infectious-allergic inflammation. Treatment with this drug resulted in prolongation of remission in increase of children’s quality of life.
Key words: children, recurrent stenosing laryngotracheitis, hypersensitivity of airways, Rybomunyl, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):36-41)
Key words: children, recurrent stenosing laryngotracheitis, hypersensitivity of airways, Rybomunyl, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):36-41)
LITERATURE REVIEW
42-47 569
Abstract
Evaluation of health state in children living in the city with developed cement industry showed presence of pre-nosological forms of ecologically conditioned diseases coming into being as a result of exposure with salts of heavy metals in cement dust.
Key words: children, cement dust, bronchial asthma, pneumoconiosis, dermatosis, crystaluria, nephropathy, gestosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):42-47)
Key words: children, cement dust, bronchial asthma, pneumoconiosis, dermatosis, crystaluria, nephropathy, gestosis.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):42-47)
LECTURES
48-54 651
Abstract
The lecture reviews modern ideas of comatose conditions: their types, etiology, common key pathogenesis elements, stages, key manifestations, treatment principles; it characterizes the specifics of certain coma varieties and key impairments of consciousness.
Key words: coma, stupor, sopor, hypoxia, impairments of energy supply for neurons.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):48-54)
Key words: coma, stupor, sopor, hypoxia, impairments of energy supply for neurons.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):48-54)
56-63 548
Abstract
The article analyzes information on the role of nutrition from the position of risk and antirisk for forming of pathology and disorders in children’s development. Author gives arguments to the use of specialized products in nutrition of children 1–3 years old.
Key words: nutrition, risk, antirisk, specialized products.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):56-63)
Key words: nutrition, risk, antirisk, specialized products.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):56-63)
EXCHANGE OF EXPERIENCE
64-66 502
Abstract
Infections of airways are one of significant causes of morbidity in children. Approximately 70% of infections affect upper airways, ear, nose and throat. The problem is special for children with allergic pathology because any intercurrent virus disease can cause exacerbation of allergy. Open uncontrolled study of effectiveness of pidotimod in children with combined forms of allergy (bronchial asthma, allergic rhinitis, atopic dermatitis) and severe acute respiratory disease was performed in 2008–2010 in Novosibirsk. Pidotimod as a component of complex treatment decreased trigger role of infections and eased clinical course of main disease. This drug decreased the rate of relapses and load of medications in patients.
Key words: children with frequent diseases, immunomudulators, pidotimod.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):64-66)
Key words: children with frequent diseases, immunomudulators, pidotimod.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):64-66)
67-71 1000
Abstract
Authors present results of treatment of 60 patients with cystic fibrosis 1–17 years old with «The Vest Airway Clearance System». Method of high-frequency oscillation of chest increases volume of moved off phlegm and improves functional abilities of lungs. This method can be used in younger children and in patients regardless of age in poor condition who can’t actively carry out drainage of phlegm and respiratory exercises.
Key words: children, cystic fibrosis, high-frequency oscillation of chest, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):67-71)
Key words: children, cystic fibrosis, high-frequency oscillation of chest, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):67-71)
72-79 596
Abstract
Development of new methods of treatment of cystic fibrosis (CF) is necessary because of severe clinical course of this disease and frequent development of rhinosinusitis in children. Rhinosinusitis in patients with CF has chronic clinical course, frequent exacerbation and it is hardly treated with traditional therapy. Authors studied effectiveness of treatment of chronic sinusitis with inhalations of dornase alfa in accessory sinuses of nose with compressor inhalator PARI LC SINUS. 23 children with severe clinical course of CF, chronic sinusitis and rhinitis remaining despite recommended treatment were observed during the study. Treatment with inhalations of dornase alfa with PARI LC SINUS had beneficial effect, and it can be recommended for inclusion in pediatric practice.
Key words: children, cystic fibrosis, chronic rhinosinusitis, dornase alfa, PARI LC SINUS, conservative therapy.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):72-79)
Key words: children, cystic fibrosis, chronic rhinosinusitis, dornase alfa, PARI LC SINUS, conservative therapy.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):72-79)
80-84 799
Abstract
Hyperthermia is the key symptom of acute respiratory infections (ARI). An increase in the body temperature is accompanied with phagocytosis activation, increased interferon synthesis, antibody genesis stimulation, lymphocytes activation and differentiation. Nevertheless, significant hyperthermia may result in my unfavourable consequences. It may particularly cause an exacerbation of chronic diseases. Modern therapy for hyperthermia is, therefore, an important aspect of treating children with ARI. The article outlines the modern approach to treating fever in children, identifies key criteria for selecting a medication. It also contains a case study of applying ibuprofen and data from various trials which verify the rationale for applying ibuprofen in children with hyperthermia that developed in conjunction with ARI.
Key words: children, acute respiratory infections, hyperthermia, ibuprofen.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):80-84)
Key words: children, acute respiratory infections, hyperthermia, ibuprofen.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):80-84)
85-89 488
Abstract
One of the largest risk groups of hypovitaminosis development are children with prolonged gastroenterological diseases. This problem is significant in infants, because they can develop prolonged enterocolitis conditioned by opportunistic micro flora which results in severe dysbacteriosis, delay of development and beginning of dystrophy. Normal micro flora is one of the sources of vitamins (especially B group). Besides, inflammation in intestine results in disorder of digestion and absorption processes, and it can break metabolism of different nutrients. Authors present results of treatment of organic intestinal diseases with syrup «Picovit».
Key words: children, enterocolitis, polyvitamins.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):85-89)
Key words: children, enterocolitis, polyvitamins.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):85-89)
A DOCTOR’S AID
90-94 648
Abstract
Children’s skin under nappy needs special defense from irritative action of urine and faeces and, therefore, prophylaxis of nappy dermatitis is necessary. It means that disposable nappy absorbing faeces and urine and special staff for skin cleaning should be used. There are several factors conductive to dermatitis: prolonged irritation with excrements, change of skin pH or increase of its hydratation and disorders of skin micro flora. During last decades there is a significant progress in understanding of these factors, and it resulted in production of more and more perfect stuff for defense of children’s skin. Improved design of nappies and development of pH-buffer wipes for babies increased the quality of skin care.
Key words: children, skin, hygienic care.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):90-94)
Key words: children, skin, hygienic care.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):90-94)
95-98 772
Abstract
Authors analyzed the data on children’s provision with calcium, which is necessary for normal growth and development. It is important to use food stuffs enriched with calcium for prophylaxis of osteopenia and osteoporosis, which are frequent in children because of intensive growth and insufficient taking of this ion with food.
Key words: children, calcium, prophylaxis of osteoporosis and osteopenia.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):95-98)
Key words: children, calcium, prophylaxis of osteoporosis and osteopenia.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):95-98)
99-102 538
Abstract
Okavax is the first vaccine (based on strain Oka) against varicella in the world. It has high immunogenicity, provides maximally prolonged defence due to forming of cell immunity. Thus, Okavax is efficient against severe varicella. Efficiency of this vaccine is confirmed with results of studies during 20 years. Okavax has good tolerability; it can be recommended to all patients after 12 months old, especially to patients from risk groups.
Key words: children, varicella, vaccination.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):99-102)
Key words: children, varicella, vaccination.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):99-102)
103-106 455
Abstract
Author presents modern scientific data on dangerous products of burning organic vegetable substances and peculiarities of its pathogenic influence on children’s organism. This data became very significant in the summer 2010. The article gives recommendation on prophylaxis and treatment of negative consequences of smoke inhalation with effective and safe children’s vitamin-mineral complexes «Alfavit» developed taking into account synergism and antagonism of different components.
Key words: products of burning, oxidant stress, vitamin-mineral insufficiency, antioxidants.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):103-106)
Key words: products of burning, oxidant stress, vitamin-mineral insufficiency, antioxidants.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):103-106)
107-110 604
Abstract
Author discusses advantages of topical antibacterial treatment of inflammatory diseases of upper airways. Advantages of new form of Bioparox (fusafungine) are rapid effect from the 1st day of treatment, optimized dosing regimen, additional children’s attachment for nose and increased adherence to therapy.
Key words: sinusitis, acute respiratory infections, pharyngitis, treatment, fusafungine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):107-110)
Key words: sinusitis, acute respiratory infections, pharyngitis, treatment, fusafungine.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):107-110)
111-116 671
Abstract
The article presents modern data on syndrome of acute diarrhea in children, its etiology and mechanisms of development of different types of this disease, its clinical symptoms, differential diagnosis, laboratory and instrumental methods of diagnostics. Author gives review of pathogenetic treatment and opportunities of therapy with enterosorbates, taking into account etiology of diarrhea. Another chapter of the article describes opportunities and methods of oral hydration depending of extent of exicosis.
Key words: acute diarrhea, children, etiology, pathogenesis, clinical symptoms, etiotropic therapy, enterosorbates, oral hydration.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):111-1116)
Key words: acute diarrhea, children, etiology, pathogenesis, clinical symptoms, etiotropic therapy, enterosorbates, oral hydration.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):111-1116)
117-120 3080
Abstract
Atopic dermatitis (AtD) is one of the most widespread types of allergic lesions of skin in children. Increase of severe types of AtD with lesion of big parts of skin, high frequency of exacerbations, presence of concomitant atopic diseases, and inefficiency of standard therapeutic approaches, torpid clinical course and early development of disability, causes an anxiety. Present standard approaches can be ineffective in children with severe clinical course of AtD and they are not able to prevent progression of disease, development of severe exacerbations and child’s disability. One of therapeutic alternatives for these patients is treatment with immunosuppressive agents. The article describes questions of treatment with cyclosporine in systemic therapy of severe resistant forms of AtD in children. Author discusses effectiveness and safety of a drug, formulated rules of treatment of severe AtD with cyclosporine.
Key words: children, atopic dermatitis, cyclosporine, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):117-120)
Key words: children, atopic dermatitis, cyclosporine, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):117-120)
121-126 3262
Abstract
Author describes peculiarities of functional (obstipational) encopresis in children with prolonged chronic constipation. Disease relates to many predisposing factors; the most significant ones are perinatal pathology, disorders of nutritional behavior, psychological traumatic experience and social disadaptation of patient. Complex rehabilitation program of children with functional encopresis allows provision of optimal medical care.
Key words: children, functional ecopresis, fecal incontinence, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):121-126)
Key words: children, functional ecopresis, fecal incontinence, treatment.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):121-126)
CLINICAL OBSERVATIONS
T.V. Sleptsova,
E.I. Alexeeva,
S.I. Valieva,
T.M. Bzarova,
A.O. Lisitsin,
K.B. Isaeva,
R.V. Denisova
127-132 476
Abstract
The article presents a case report of severe polyarticular juvenile rheumatoid arthritis (JRA) resistant to treatment with corticosteroids and classic immunosuppressive agents. Authors describe successful treatment with genetically engineered biological agent — infliximab in patient with early arthritis (duration of disease in less than two years): at 1st week of treatment pain and morning stiffness were stopped, and exudative lesions of joint significantly decreased. Inactive phase of disease was reached in 6 weeks, and movements in 8 of 9 joints were restored. Oral prednisolone was stopped. This case report shows high effectiveness of infliximab in patient with early JRA. Therapeutic treatment of early stages of disease before development of irreversible osteocartilaginous destruction with blocker of tumor necrotizing factor is very perspective.
Key words: children, early juvenile rheumatoid arthritis, treatment, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):127-132)
Key words: children, early juvenile rheumatoid arthritis, treatment, infliximab.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):127-132)
SHORT REPORTS
HISTORY OF PEDIATRICS
138-141 1357
Abstract
Authors describe family relations and traditions of Chechens in Ingush from ancient times to present (traditional obstetrics, delivery ceremonies, child’s management and feeding) and make a conclusion that family was and now is basic social institute of these nations. These people saved traditional way of living and norms of demographic behavior to the highest degree then other nations in Russia. High prevalence and prolonged period of breast feeding in Chechen and Ingush Republics (compared to other districts of Russian Federation) can be explained by their cultural and ethnical peculiarities.
Key words: breast feeding, Chechen, Ingush, national tradition, obstetrics service, childhood.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):138-141)
Key words: breast feeding, Chechen, Ingush, national tradition, obstetrics service, childhood.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(5):138-141)
ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)
ISSN 1682-5535 (Online)
