Vol 7, No 3 (2008)
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SOCIAL PEDIATRICS AND HEALTH CARE
6-8 551
Abstract
The results of structural modification in pediatric and obstetric services were described in this work. This modification was directed to the increase of a quality of medical care to women and children and to the realization of priority national project «health».
Key words: restructuring, children, pregnant women, infant mortality.
Key words: restructuring, children, pregnant women, infant mortality.
9-12 492
Abstract
The assessment of the efficacy of application of the modern communicatory technologies in children's city out patient clinics was presented in this article. Communicatory technologies in out patient clinics could help to solve three fundamental problems: medical, social and economical.
Key words: communicatory technologies, children, children's out patient clinic, electronic outpatient's card.
Key words: communicatory technologies, children, children's out patient clinic, electronic outpatient's card.
13-16 841
Abstract
The structure and causes of maternal mortality in younger women (n = 50) in the Russian federation in 2002–2006 years was analyzed. About 8% of women died before 28 week of pregnancy, 66% of women died during labor and in postpartum period, cause of death in 26% of patients was the abortion before 28 week of pregnancy. The most frequent causes of maternal mortality in younger women are gestosis (in 30% of patients), extragenital diseases (in 26% of patients), and septic complications (in 20% of patients). The quality of medical care was analyzed. Proved, that interaction between obstetrician gynecologist and pediatricians, psychologists and social workers and prophylaxis of unwanted pregnancy in adolescents is essential to prevent maternal mortality in younger women. Prophylactic measures must be directed to active pregnancy finding in young women, early registering, and close observation and following delivery in perinatal centers or specialized maternity hospitals.
Key words: younger women, maternal mortality, prophylaxis.
Key words: younger women, maternal mortality, prophylaxis.
17-19 680
Abstract
The data on level and structure of morbidity in adolescents, depending on place of living, social history of their families, age and sex was presented in this article. This data was obtained from results of preventive examination in younger and older adolescents. Authors of trial suggest varied approach to growth and development observation of adolescents, depending on place of their living.
Key words: adolescents, morbidity, aboriginal population, migrants.
Key words: adolescents, morbidity, aboriginal population, migrants.
20-23 474
Abstract
The priority of breast feeding was observed taking into account a demographic setting in our country at present. The role of maternity and childhood protection services in Buryat republic in popularization of breast feeding was shown. The need of further introduction of new organizational technologies in improvement of health state of newborns was noted.
Key words: breast feeding, maternity and childhood protection services, organizational technologies.
Key words: breast feeding, maternity and childhood protection services, organizational technologies.
ORIGINAL ARTICLES
26-32 528
Abstract
Lipid composition in children with different types of juvenile arthritis was investigated in this trial. Significant decrease of plasma concentration of cholesterol in high density lipoproteins in patients with high activity of rheumatoid arthritis was discovered. «Atherogenic» shift of lipid composition and increase of atherogenity index was shown in most of pediatric patients with different types of juvenile arthritis. The number of children with increased atherogenity index grows according to the increase of disease activity. pediatric patients with high activity of juvenile arthritis and juvenile ankylosing spondylitis are the risk group of early atherosclerosis development.
Key words: juvenile arthritis, atherosclerosis, high density lipoproteins, triglyceride, atherogenity index.
Key words: juvenile arthritis, atherosclerosis, high density lipoproteins, triglyceride, atherogenity index.
33-37 526
Abstract
This work focuses on characteristics of central and peripheral hemodinamics and its correlation with 24 hours' profile of blood pressure and humoral status in adolescents with primary arterial hypertension. 91 adolescent was examined, 27 patients had phenomenon of white coat hypertension, other patients had labile (n = 37) and stable (n = 27) arterial hypertension. Maximal value of myocardial mass of left ventricle was in adolescents with stable arterial hypertension. The signs of remodeling of myocardium of left ventricle were stated in 6 (6,5%) patients. the intensity of hypertrophy of left ventricle concerned with high variability of systolic blood pressure during daylight hours and its inadequate reduction during a night. Indices of central and peripheral hemodynamics in a number of cases associated with humoral factors — concentration of uric acid and willebrand factor in blood plasma.
Key words: adolescents, arterial hypertension, heart remodeling, uric acid, willebrand factor.
Key words: adolescents, arterial hypertension, heart remodeling, uric acid, willebrand factor.
38-42 948
Abstract
Embarrassment of left renal and common iliac veins is a congenital abnormality of veins. In single patients this abnormality can lead to regional venous hypertension. Diagnosis and treatment of this state in pediatric practice are not developed. Adolescent patients (n = 61) with embarrassment of left iliac or/and renal veins were treated in 2002–2006 years. The main signs of embarrassment were: varicocele, dilatation of subcutaneous veins and edema of left leg, proteinuria, microhematuria, pain in left renal area. Ultrasonic doppler and renophlebography with phlebotonometry were used in all patients. Indication to different types of surgical procedures, depending on angiographic data and intensity of blood supply disturbance were developed. The intensity of blood supply was measured with pressure gradient. 61 surgical procedures were carried out with the control of intra operative phlebotonometry. Decrease of blood pressure gradient in left renal and iliac veins was chosen as an efficacy criterion. All treated patients had a significant decrease of blood pressure gradient in left renal and iliac veins.
Key words: adolescents, venous hypertension, renal veiniliac vein, iliac artery, embarrassment syndrome.
Key words: adolescents, venous hypertension, renal veiniliac vein, iliac artery, embarrassment syndrome.
LITERATURE REVIEW
44-51 794
Abstract
Allergen specific immunotherapy (ASIT) is a very effective technique in treatment of many allergic diseases. It greatly improves the quality of life. There's a risk of adverse system reactions at the time of ASIT. Treatment with anti Ige antibodies (omalizumab, xolair) allows decreasing the circulating Ige level and lessening an expression of high affinity fc_r1 receptors on the surface of basophiles and mast cells, inhibition of early and late phase of allergic inflammatory response. Combination of antibige therapy and ASIT can lead to decrease of risk of adverse system reactions.
Key words: omalizumab, anti Ige antibodies, allergen specific immunotherapy.
Key words: omalizumab, anti Ige antibodies, allergen specific immunotherapy.
52-57 910
Abstract
The data of a prevalence and etiology of main ENT infectious in children was presented in this work. The methods of choice of antibacterial medications in management of acute and chronic otitis media, acute and chronic sinusitis, acute and recurrent tonsillopharyngitis, epiglottitis were reviewed. Special accent was given to the opportunity of management of these diseases with cephalosporins and, particularly cefixime (suprax). Cefixime is peroral cephalosporin of iii generation; it combines wide range of antibacterial activity, good pharmacokinetic characteristics, favorable tolerance and comfortable application (it should be prescribed once daily). The data, obtained from many controlled trials, shows high clinical and microbiological activity of cefixime in management of ENT infections in children.
Key words: children, ENT infections, cefixime, treatment.
Key words: children, ENT infections, cefixime, treatment.
58-65 573
Abstract
The data from 12 randomized controlled trials (over 4 thousand of children with known anthropometric data), investigating efficacy of supplement of vitamins and minerals in complex drug to the increase of height and weight in children were included. Proved that routine prescription of micronutrients is accompanied by increase of children's height — standardized mean difference (smd) was 0,28 (95% ci — 0,09; 0,47) (р = 0,003). Maximal efficacy of micronutrients supply was registered in subgroup of stunted children with heightbage zbscores (haz) < b2,0 — SMD 0,58 (0,33; 0,84) (p < 0,001) and in children over 5 years — SMD 0,42 (0,07; 0,78) (р = 0,02). micronutrients don't affect body weight, HAZ, WAZ (weightbage zbscores) and WHZ (weight height zbscores). The results of trials were heterogeneous. The reasons of heterogeneity were a difference in age of children, growth and body weight dynamics, and duration of trial. This metabanalysis indicates that routine micronutrients supply doesn't affect children's body weight, but favors to increase of their growth compared to placebo. Micronutrients show maximal activity in stunted children.
Key words: children, micronutrients, height, weight, meta analysis.
Key words: children, micronutrients, height, weight, meta analysis.
LECTURES
66-75 1568
Abstract
The main aspects of iodine metabolism in human organism, physiological need in this microelement, prevalence and criteria of diagnosis of iodine deficient diseases are presented in this article. The measures, essential to the iodine deficiency prophylaxis are described, and possible choices of compensation of iodine deficiency in provisions, including milk formulas, are discussed. recommendations of international expert medical societies, giving evidence of prophylaxis of thyroid gland diseases, related with iodine deficiency, are presented.
Key words: children, iodine, prophylaxis.
Key words: children, iodine, prophylaxis.
EXCHANGE OF EXPERIENCE
76-78 690
Abstract
The article focuses on the analysis of experience of differential diagnosis of bacterial and viral lymphadenitis in children. Diagnostics of different types of lymphadenitis in 70 pediatric patients was carried out with procalcitonin detection in blood plasma, held by immunochromatographic expressbtesting (brahms PCT Q).
Key words: procalcitonin, viral lymphadenitis, bacterial lymphadenitis.
Key words: procalcitonin, viral lymphadenitis, bacterial lymphadenitis.
E.I. Alexeeva,
E.L. Semikina,
T.M. Bzarova,
S.I. Valieva,
R.V. Denisova,
A.O. Lisitsin,
E.Yu. Gudkova,
S.S. Akulova,
E.A. Kopyl'tsova
79-85 469
Abstract
The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of disease were stopped by 6 week of treatment, and acute inflammatory alteration of articulations was reduced by 16 week, the range of motions was completely restored. This case report demonstrates high activity of rituximab. A clinical and laboratory remission of disease in patient with severe course of systemic juvenile rheumatoid arthritis continues for a 32 weeks.
Key words: children, juvenile rheumatoid arthritis, rituximab.
Key words: children, juvenile rheumatoid arthritis, rituximab.
A DOCTOR’S AID
86-90 488
Abstract
The number of vacationists on resorts of Krasnodar region exceeded 12 million in 2007 year. More then 500 thousands of vacationists were children in organized groups. Because of well coordinated work of hygiene and disease prevention and pediatric services of region the number of cases of pertussis, measles, rubella, epidemic parotiditis, hepatitis A and B and other infectious diseases, dirigible with specific prophylactic measures, was greatly decreased. The opportunity of vaccinal prevention of varicella appears by 2008 year. It's advisable to make a hepatitis a vaccination of children, arriving from endemic regions, domiciliary. «Delivered» cases of disease cause significant economical damage to the budget of public health service of Krasnodar region. Preliminary planning of a journey and assumption of prophylactic measures can greatly decrease the risk of negative influence of trip on child's health.
Key words: children, vaccination, prophylaxis, infectious disease.
Key words: children, vaccination, prophylaxis, infectious disease.
91-94 1341
Abstract
The article focuses on theoretical and practical aspects of using acetylaminosuccinic acid (cogitum) in neuropediatrics. General properties of amino acid drugs were discussed. Special attention was attributed to chemical and biophisiological features, metabolism and principles of activity in CNS of aspartic acid. Pharmacological properties of acetylaminosiccine acid, official indications for its use provided by manufacturers plus others (pathology according to icdb10), contraindications, adverse reactions, and peculiarities of dosage and treatment regimen were described.
Key words: acetylaminosiccine acid, aspartic acid, children, neuropediatry, neurodietology.
Key words: acetylaminosiccine acid, aspartic acid, children, neuropediatry, neurodietology.
95-98 466
Abstract
The results of trials, investigating a tolerance to juices in children were summarized in this work. The correlation between criteria of tolerance and concentration of carbohydrates and osmolarity of juice was proved. Authors reviewed present guidelines on nutrition with juices in children of first year of life as a lure.
Key words: juices, children's nutrition, lure.
Key words: juices, children's nutrition, lure.
99-102 604
Abstract
The article focuses on the modern conception of etiology, pathogenesis and diagnostics of chronic constipation in children. a classification of laxative medications was posed and the place of these drugs in management of constipation was shown in this work. An activity of macrogol in management of children with chronic constipation was evaluated. It was shown that macrogol 4000 is effective in treatment of constipation in children.
Key words: children, chronic constipation, macrogol 4000.
Key words: children, chronic constipation, macrogol 4000.
103-105 502
Abstract
Pneumococcal infection is the most frequent cause of diseases of upper and inferior airways and nasopharynx in children. Also pneumococcal infection may cause such severe diseases as meningitis and pneumonia. The only way of prophylaxis of these diseases is vaccination. Prevalence of pneumococcal infection is analyzed and necessity of children's vaccination is proved in this article. Besides, authors present the data of new conjugated heptavalent pneumococcal vaccine, which can be used in children from 2 month in contrast to polysaccharide one.
Key words: children, pneumococcal infection, meningitis, otitis, pneumococcal conjugated vaccine.
Key words: children, pneumococcal infection, meningitis, otitis, pneumococcal conjugated vaccine.
108-112 880
Abstract
The onset of disseminated sclerosis occurs in childhood and juvenile age in 10% of patients. nevertheless, all immunomodulatory drugs for a treatment of this disease intended for adult population of patients, and there's an age limitation to the administration of these medications. There's only one interferon beta in group of «changing the clinical course of disseminated sclerosis medications», that was annotated to the administration in patients from 16 years. It's interferon betab1a (Rebif) for subcutaneous administration in 22 ?g and 44 ?g dosage. This drug was well known as an effective and safe medication for a long term administration for a long time in adult neurological practice. But doctors have to use interferon betab1a «off label» yet in patients younger 16 years in Russia and in other countries, comparing risk of changing the regimen of age limitation and risk of deprivation of un derbaged patient of years of qualitative life.
Key words: children, disseminated sclerosis, interferon beta 1a, treatment.
Key words: children, disseminated sclerosis, interferon beta 1a, treatment.
CLINICAL OBSERVATIONS
113-116 544
Abstract
The case report of spontaneous carpalbtarsal osteolysis in 11byearbold boy is presented in this article. The attention draw to the rarity of this disease, the literature data of spontaneous osteolysis was given. The features of clinical presentation were described, and need of differential diagnosis with juvenile rheumatoid arthritis was proved.
Key words: spontaneous carpal tarsal osteolysis, differential diagnosis.
Key words: spontaneous carpal tarsal osteolysis, differential diagnosis.
INFORMATION FROM THE UNION OF PEDIATRICIANS OF RUSSIA
SHORT REPORTS
HISTORY OF PEDIATRICS
ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)
ISSN 1682-5535 (Online)
