Vol 7, No 5 (2008)
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SOCIAL PEDIATRICS AND HEALTH CARE
6-10 602
Abstract
Adaptative resources of children's organisms at the time of their entrance to school were evaluated with modern automated technology — the method of computer dermographia (KD). Significant risk factors of negative course of adaptative process were determined. High self descriptiveness of KD for integral estimation of state of health at the time of adaptation of children to the school conditions was demonstrated. The scheme of prophylactic measures was developed for the purpose of improvement of state of health of children in preschool age and minimization of negative effects of adaptational period.
Key words: adaptation, first formers, computer dermographia.
Key words: adaptation, first formers, computer dermographia.
11-14 590
Abstract
405 students of secondary school in Moscow, Kaliningrad and Murmansk took part in the testing. The correlation between poor health in students and mode of their living was shown. It's recommended to create unified standard of students education in the field of hygiene, breeding and healthy life style.
Key words: secondary school students, health, life style.
Key words: secondary school students, health, life style.
16-19 513
Abstract
The dynamics of rates of maternal, infant and perinatal mortality in Russian federation is presented in this article. The reasons of infant mortality were analyzed. The results of realization of federal principal program «children of Russia» and subprogram «healthy child» in 2003–2006 years, and measures of priority state project in health service sphere in directions «neonatal screening» and «delivery certification» were given. For the purpose of further decrease of rates of maternal and infant mortality it is necessary to strengthen a material and technical basis of institutions of maternity and childhood, to create a system of perinatal centers, to raise an accessibility of high tech types of medical service, to organize training of personnel, to develop a prophylactic direction of medical service.
Key words: maternal mortality, infant mortality, neonatal screening, high tech medical service.
Key words: maternal mortality, infant mortality, neonatal screening, high tech medical service.
ORIGINAL ARTICLES
20-22 597
Abstract
In order to assess the efficacy of two immunostimulant treatments for prevention of recurrent pharyngotonsillitis, a controlled, parallel group clinical study was conducted. 40 subjects, adults and children, with a positive history of at least acute, febrile, infectious episodes in the oropharyingeal region, were randomized to treatment with pidotimod or with lyophilized polybacterial lysates (LPL). 90 days after the start of treatment, the pidotimod group showed a significant in crease in multitest response by comparison to the LPL group. During the observation period, moreover, a significantly lower incidence of infectious episodes was seen in the pidotimod group than in the LPL group. Tolerance and compliance were good for both drugs.
Key word: recurrent pharyngotonsillitis, pidotimod, treatment.
Key word: recurrent pharyngotonsillitis, pidotimod, treatment.
23-26 542
Abstract
The pathogenetic approach to treatment of symptoms of normal vaccinal process in children after standard vaccination, based on the results of application of anti9inflammatory medications — ibuprofen (nurofen for children) and paracetamol is presented in this article. Clinical activity of ibuprofen was established on the basis of clinica catamnestic observation of 856 vaccinated children aged from 3 months to 3 years. recommendations for application of these medications as a treatment for a correction of vaccinal reactions are given.
Key words: children, ibuprofen, paracetamol, vaccination.
Key words: children, ibuprofen, paracetamol, vaccination.
27-33 705
Abstract
950 schoolchildren in Omsk were observed for the purpose of detection of signs of connective tissue dysplasia (CTD). An intensity of symptoms of CDT, vegetative dysfunction, psycho emotional status were estimated with following correction of these disorders with magnesium orotate (marnerot). The symptoms of CTD were detected in more then a half of children and adoles cents with maximal detectability in age of 13–17 years old. An influence of sympathetic system on vegetative status was registered in children and adolescents. Typical signs of it were discoordinated vegetative regulation of respiratory and cardio vascular systems, disorder of psycho emotional status (instability in uneasiness factor, factor of instability of choice, factor of capacity of work). Treatment with magnesium orotate in children and adolescents with CDT was followed by positive changes of state of health, decrease of symptoms of vegetative disbalance, normalization of psycho emotional status, mainly due to restoration of capacity to work.
Key words: children, adolescents, connective tissue dysplasia, vegetative dysfunction, magnesium orotate.
Key words: children, adolescents, connective tissue dysplasia, vegetative dysfunction, magnesium orotate.
34-38 667
Abstract
The paper is dedicated to the problem of cognitive dysfunctions in pediatric patients with rolandic epilepsy (benign partial epilepsy of childhood). Russian nootropic drug pantoham (hopantenic acid) was used for correction of cognitive deficit. Quantitative data obtained via psihomat testing computer system were utilised for verification of principle cognitive functions before and after treatment with hopantenic acid in school age patients undergoing basic antiepileptic therapy. Positive effect of the drug on studied cognitive functions' indices was demonstrated.
Key words: children, epilepsy, cognitive functions, hopantenic acid.
Key words: children, epilepsy, cognitive functions, hopantenic acid.
R.V. Denisova,
V.Yu. Al'bitsky,
E.I. Alexeeva,
I.V. Vinyarskaya,
S.I. Valieva,
T.M. Bzarova,
A.O. Lisitsin,
E.Yu. Gudkova,
K.B. Isaeva,
A.M. Chomakhidze
39-45 820
Abstract
Quality of life is one of the principal criteria of efficacy of medical treatment of juvenile rheumatoid arthritis (JRA). There's no any questionnaire for the estimation of quality of life in children aged from 2 to 4 years old in Russia today. Questionnaire chaq (childhood health assessment questionnaire) can be useful for only estimation of functional status in children with JRA. A reliability, validity and sensitivity of Russian versions of ped SQL rheumatology module and ped SQL generic core scale questionnares for the estimation of quality of life in children aged from 2 to 4 years old with JRA are valued in this article. The value of chronbach's alpha was from 0,71 to 0,95, this is an evidence of reliability of Russian version of ped SQL questionnaire. Significant inverse negative relationship of quality of life rate and activity of disease and functional insufficiency index confirms validity of Russian versions of ped SQL questionnaires. Significant increase of quality of life rate in children with JRA aged from 2 to 4 years old treated with infliximab can confirm high sensitivity of Russian versions of ped SQL questionnaires. Authors made a conclusion that Russian versions of ped SQL questionnaires allow estimating quality of life in children with JRA aged from 2 to 4 years old.
Key words: children, juvenile rheumatoid arthritis, quality of life, ped SQL rheumatology module, ped SQL generic core scale, infliximab.
Key words: children, juvenile rheumatoid arthritis, quality of life, ped SQL rheumatology module, ped SQL generic core scale, infliximab.
S.V. Zaitseva,
O.V. Zaitseva,
N.V. Aleksandrina,
T.V. Praznikova,
T.I. Rychkova,
S.I. Bardennikova,
E.V. Kulikova,
O.B. Dovgun,
M.A. Kazantseva,
O.B. Voronina,
T.P. Rubtsova
46-50 689
Abstract
Efficacy and safety of long acting 29 agonist formoterol (foradil aerolizer) was investigated in comparative study. 30 pediatric patients (6–16 years old) with bronchial asthma were treated with formoterol. 100 ?g of salbutamol by metered9dose inhaler was administered to control group of children (n = 30). The bronchodilating effect of formoterol was comparable to that of short acting 29 agonist salbutamol. Maximal bronchodilating action was registered in 2–4 hours after inhalation and lasted out more then 12 hours. For moterol aerolizer can be easily applicated and allows to carry out doctor's recommendations and to increase the effectiveness of treatment. Formoterol aerolizer allows making greatly less mistakes in inhalation technique then salbutamol in metered dose inhaler. Authors made a conclusion that for moterol can be used as a rescue treatment in children with bronchial asthma upwards 5 years old treated with appropriate basis regimens.
Key words: children, bronchial asthma, formoterol, aerolizer.
Key words: children, bronchial asthma, formoterol, aerolizer.
LITERATURE REVIEW
51-56 621
Abstract
The theme of review is the results of treatment of rheumatic diseases in adults and children with blocker of TNF-α etanercept. The data from single, open-labeled and multicenter double blinded placebo-controlled studies of activity and safety of etanercept is presented in this article. The results of researches show high efficacy of etanercept in treatment of rheumatoid arthritis and ankylosing spondylitis in children and adults. Besides high activity etanercept is one of the safest blockers of TNF-α in pediatric and adult practice.
Key words: children, juvenile rheumatoid arthritis, treatment, etanercept.
Key words: children, juvenile rheumatoid arthritis, treatment, etanercept.
58-70 822
Abstract
The modern state of a problem of nutrition in pregnant women and nursing mothers is discussed and the ways of correction of nutrition with specialized milk formulas and vitamin mineral complexes are described.
Key words: pregnant, nursing mothers, nutrition, vitamin mineral complexes.
Key words: pregnant, nursing mothers, nutrition, vitamin mineral complexes.
71-74 988
Abstract
The data of different firms of hereditary galactosemia was analyzed in this article. Clinical and biochemical characteristics and molecular and genetic features of diagnostics of this disease were described. The information about differential diagnosis and problems, related with hereditary galactozemia screening in Russia was given.
Key words: children, galactosemia, treatment, screening.
Key words: children, galactosemia, treatment, screening.
76-81 995
Abstract
According to modern data, calcium insufficiency in children is actual problem of pediatrics. Information about calcium function, its metabolism, and the questions of influence of calcium on bone tissue and regulation of phosphorus calcium exchange is presented in this article. Special attention is given to problem of calcium insufficiency in children and its prophylaxis, including treatment with vitamin and mineral complexes. The data from study of «calcinova» in treatment of different disorders in children is presented.
Key words: children, calcium, insufficiency, vitamin d, prophylaxis.
Key words: children, calcium, insufficiency, vitamin d, prophylaxis.
82-86 576
Abstract
The results of trials studying influence of uncombined vitamin a and complex micronutrients containing retinol on children's body weight are analyzed in this article. Uncombined vitamin a doesn't influence on this rate. Micronutrients containing vitamin a administrated during 6 months (median) cause moderate but significant increase of body weight in children. This effect very largely concerned with increase of vitamin a concentration in blood plasma per 1,18 (0,12; 0,23) mol/l or almost 20% from reference level. The study of results of meta-analysis showed that this result can be achieved with administration of 450 g of vitamin a daily (333–526 g daily) in complex with other micronutrients.
Key words: children, body weight, vitamin a, meta analysis.
Key words: children, body weight, vitamin a, meta analysis.
87-90 511
Abstract
The review of safety of monoclonal anti-ige-antibodies (xolair) — a new medication for the treatment of severe allergic bronchial asthma is presented. Local and system adverse events, originating after injection of medicament in clinical studies and following administration in patients are discussed.
Key words: children, bronchial asthma, monoclonal anti Ige antibodies.
Key words: children, bronchial asthma, monoclonal anti Ige antibodies.
LECTURES
91-97 1797
Abstract
Acute epiglottitis (AE) must be considered as not a separate entdisease but as compound pathology with wide polymorphism, which can often need an intervention of different medical specialists: experts in resuscitation, infectiologists, immunologists, pulmonologists, and cardiologists. The increase of rate of AE and its septic complications and severe outcomes in last years forced us to consider this problem in detail on the basis of longstanding experience of Morozov children's city clinical hospital.
Key words: children, acute epiglottitis, etiology, diagnosis, treatment.
Key words: children, acute epiglottitis, etiology, diagnosis, treatment.
EXCHANGE OF EXPERIENCE
98-100 2033
Abstract
Biochemical analysis of children's blood with posthypoxic myocardial ischemia shows increase of creatine phosphokinase (CPK), lactate dehydrogenase (LDH) and troponin. The search of optimal methods of correction posthypoxic myocardial pathology is lasts. Authors examined 104 newborns of first day of living. 83 children had perinatal hypoxia and were observed in children republic clinical hospital of ministry of public health of Tatarstan republic. 62 patients received classical therapy (group 1), and the rest of children received treatment with dimephosphon (group 2). Control group 3 consists of 21 relatively healthy newborns. The activity of LDH, CPK and Troponin (TNI) was registered in all children. Besides, a registration of electrocardiogram (ECG) as provided. destabilization of electrical activity of myocardium and increase of cardio tropic enzymes activity and blood concentration of TNI was estimated as consequences of hypoxia. The level of TNI had a tendency to increasing in children, the state of who was severe at the time of admission. The results of study demonstrate significantly higher therapeutic effect on the assumption of addition of dimephosphon to the standard course of treatment.
Key words: newborns, hypoxia, troponin I, creatine phos phokinase, lactate dehydrogenase, electrocardiography.
Key words: newborns, hypoxia, troponin I, creatine phos phokinase, lactate dehydrogenase, electrocardiography.
101-104 510
Abstract
High prevalence of urinal infections (UI) in children, high rate of relapse and increase of antibiotic resistance force specialists to search a new complex methods of anti relapse therapy. Analysis of 380 medical cards of children showed that phytotherapy is not always used correctly; in spite of it can be important part of anti relapse therapy. The activity of different schemes of treatment of UI with phytomedicament «canephron n» included in it was studied in 110 children (aged from 5 month to 15 years). Children treated with complex therapy with antibiotics and phytomedication had no relapse in 99% of cases in 6 months and in 91% in 1 year follow up.
Key words: children, urinal infections, phytotherapy.
Key words: children, urinal infections, phytotherapy.
CLINICAL OBSERVATIONS
105-109 948
Abstract
The article represents an analysis of 38 events of inborn heart diseases of fetus with nuchal translucency, diagnosing on 11–16 weeks of pregnancy during consultative procedure. The spectrum of registered inborn heart diseases is represented by following nosologic forms: defect of interventricular partition, heart ectopy, atrioventricular canal, general arterial trunk, hypoplastic syndrome of the left sections of heart, fallot's tetrad, combination of defects of intracardiac partitions with diverticulum of ventricle. Frequency of registered inborn heart diseases and negative perinatal outcomes increased with the rise of thickness of nuchal translucency of fetus. transvaginal echocardiography with use of highly resolving ultra sonic equipment and new technology should be carried out in all cases of registration of widened nuchal translucency of fetus. It is decisive in improvement of diagnostics of inborn heart diseases, especially on early terms.
Key words: inborn heart diseases, transvaginal echocardiography, prenatal diagnostics.
Key words: inborn heart diseases, transvaginal echocardiography, prenatal diagnostics.
110-114 559
Abstract
A case report on a severe course of juvenile seronegative polyarthritis is presented in this article. Successful treatment with «zinaxin» containing glucosamine and extracts of zingiber officinale, made with lipocap technology as an alternative to nonsteroidal anti9inflammatory drugs was performed is patient with developed adverse event to the medicaments (increase of plasma levels of alanine aminotransferase and aspartate amino transferase five times a much compared to norm), combined with quadrotherapy of duodenal ulcer. Patient had a good status, pain syndrome and morning joint stiffness were absent during treatment with «zinaxin with glucosamine» daily and dsintoxication course (2 months) in conditions of withdrawal of immunosuppressive treatment. activity of disease had 0–1 grade according to examination data.
Key words: children, juvenile arthritis, pain syndrome.
Key words: children, juvenile arthritis, pain syndrome.
A.O. Lisitsin,
E.I. Alexeeva,
T.M. Bzarova,
S.I. Valieva,
A.M. Chomakhidze,
K.B. Isaeva,
E.G. Chistyakova,
R.V. Denisova,
E.Yu. Gudkova,
N.A. Karagulyan
115-120 472
Abstract
A case report of early debut and severe course of juvenile poly arthritis with eyes lesion refractory to classic immuno suppressive agents is presented in this article. Successful application of biological agent adalimumab is described: acute inflammatory alterations in affected joints were stopped by 49 the week. Range of motions in affected joints was recovered. The remission of veitis, normalization of indicators of disease activity (ESR, concentration of creactive protein in blood plasma) was registered by 89 th week.
Key words: children, juvenile rheumatoid arthritis, rheumatoid uveitis, adalimumab.
Key words: children, juvenile rheumatoid arthritis, rheumatoid uveitis, adalimumab.
A DOCTOR’S AID
121-124 1755
Abstract
The most usable medications in pediatric practice are laxative medicaments on the basis of polyethylene glycol (Macrogol 4000) and lactulose. Macrogol 4000 (Forlax) and lactulose have rela tively equal activity, but the first one has more predictable effect (has linear dependence dose–effect), has a beneficial activity in the presence of pain syndrome and mucoprotective activity, stimulates appetite. Significant feature of lactulose is its prebiotic activity, and this is the reason of indistinctive dose–effect dependence, presence of latency time and some adverse events; the rate of last ones is low. Authors make a conclusion that the specialist can make a choice of medication, paying attention to peculiarities of disease in every single patient.
Key words: children, laxative medicaments, Macrogol 4000.
Key words: children, laxative medicaments, Macrogol 4000.
SHORT REPORTS
HISTORY OF PEDIATRICS
JUBILEE
ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)
ISSN 1682-5535 (Online)
